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Found 299 results
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Title
Type
Year
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Author
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Elemento, Olivier
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2016
Rennert H
,
Eng K
,
Zhang T
,
Tan A
,
Xiang J
,
Romanel A
,
Kim R
,
Tam W
,
Liu Y-C
,
Bhinder B
et al.
. 2016.
Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care.
.
NPJ Genom Med. 1
Allen JE
,
C Kline LB
,
Prabhu VV
,
Wagner J
,
Ishizawa J
,
Madhukar N
,
Lev A
,
Baumeister M
,
Zhou L
,
Lulla A
et al.
. 2016.
Discovery and clinical introduction of first-in-class imipridone ONC201.
.
Oncotarget. 7(45):74380-74392.
Vazirani RP
,
Verma A
,
L Sadacca A
,
Buckman MS
,
Picatoste B
,
Beg M
,
Torsitano C
,
Bruno JH
,
Patel RT
,
Simonyte K
et al.
. 2016.
Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance.
.
Diabetes. 65(6):1577-89.
Beltran H
,
Prandi D
,
Mosquera JMiguel
,
Benelli M
,
Puca L
,
Cyrta J
,
Marotz C
,
Giannopoulou E
,
Chakravarthi BVSK
,
Varambally S
et al.
. 2016.
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer.
.
Nat Med. 22(3):298-305.
Poulos MG
,
Ramalingam P
,
Gutkin MC
,
Kleppe M
,
Ginsberg M
,
Crowley MJP
,
Elemento O
,
Levine RL
,
Rafii S
,
Kitajewski J
et al.
. 2016.
Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis.
.
Nat Commun. 7:13829.
Liu Y
,
Giannopoulou EG
,
Wen D
,
Falciatori I
,
Elemento O
,
C Allis D
,
Rafii S
,
Seandel M
. 2016.
Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells.
.
Nat Commun. 7:11275.
Xylinas E
,
Hassler MR
,
Zhuang D
,
Krzywinski M
,
Erdem Z
,
Robinson BD
,
Elemento O
,
Clozel T
,
Shariat SF
. 2016.
An Epigenomic Approach to Improving Response to Neoadjuvant Cisplatin Chemotherapy in Bladder Cancer.
.
Biomolecules. 6(3)
Béguelin W
,
Teater M
,
Gearhart MD
,
Fernández MTeresa Cal
,
Goldstein RL
,
Cárdenas MG
,
Hatzi K
,
Rosen M
,
Shen H
,
Corcoran CM
et al.
. 2016.
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.
.
Cancer Cell. 30(2):197-213.
Pritchard CC
,
Mateo J
,
Walsh MF
,
De Sarkar N
,
Abida W
,
Beltran H
,
Garofalo A
,
Gulati R
,
Carreira S
,
Eeles R
et al.
. 2016.
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
.
N Engl J Med. 375(5):443-53.
Elemento O
. 2016.
KLF4: A new player in plasma cell development.
.
Cell Cycle. 15(20):2691-2.
Bunting KL
,
T Soong D
,
Singh R
,
Jiang Y
,
Béguelin W
,
Poloway DW
,
Swed BL
,
Hatzi K
,
Reisacher W
,
Teater M
et al.
. 2016.
Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region.
.
Immunity. 45(3):497-512.
Dardenne E
,
Beltran H
,
Benelli M
,
Gayvert K
,
Berger A
,
Puca L
,
Cyrta J
,
Sboner A
,
Noorzad Z
,
MacDonald T
et al.
. 2016.
N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
.
Cancer Cell. 30(4):563-577.
Takemoto A
,
Kawashima SA
,
Li J-J
,
Jeffery L
,
Yamatsugu K
,
Elemento O
,
Nurse P
. 2016.
Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis.
.
J Cell Sci. 129(6):1250-9.
Carty MA
,
Elemento O
. 2016.
Practical Analysis of Genome Contact Interaction Experiments.
.
Methods Mol Biol. 1418:177-89.
Nwachukwu JC
,
Srinivasan S
,
Zheng Y
,
Wang S
,
Min J
,
Dong C
,
Liao Z
,
Nowak J
,
Wright NJ
,
Houtman R
et al.
. 2016.
Predictive features of ligand-specific signaling through the estrogen receptor.
.
Mol Syst Biol. 12(4):864.
Sboner A
,
Elemento O
. 2016.
A primer on precision medicine informatics.
.
Brief Bioinform. 17(1):145-53.
Crowley MJP
,
Scognamiglio T
,
Liu Y-F
,
Kleiman DA
,
Beninato T
,
Aronova A
,
Liu H
,
Jhanwar YS
,
Molina A
,
Tagawa ST
et al.
. 2016.
Prostate-Specific Membrane Antigen Is a Potential Antiangiogenic Target in Adrenocortical Carcinoma.
.
J Clin Endocrinol Metab. 101(3):981-7.
Cárdenas MG
,
Yu W
,
Béguelin W
,
Teater MR
,
Geng H
,
Goldstein RL
,
Oswald E
,
Hatzi K
,
Yang S-N
,
Cohen J
et al.
. 2016.
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.
.
J Clin Invest. 126(9):3351-62.
Redmond D
,
Poran A
,
Elemento O
. 2016.
Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq.
.
Genome Med. 8(1):80.
Boi M
,
Todaro M
,
Vurchio V
,
Yang SNing
,
Moon J
,
Kwee I
,
Rinaldi A
,
Pan H
,
Crescenzo R
,
Cheng M
et al.
. 2016.
Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes.
.
Oncotarget. 7(48):79637-79653.
2017
Valls E
,
Lobry C
,
Geng H
,
Wang L
,
Cardenas M
,
Rivas M
,
Cerchietti L
,
Oh P
,
Yang SNing
,
Oswald E
et al.
. 2017.
BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells.
.
Cancer Discov. 7(5):506-521.
Pyenson NC
,
Gayvert K
,
Varble A
,
Elemento O
,
Marraffini LA
. 2017.
Broad Targeting Specificity during Bacterial Type III CRISPR-Cas Immunity Constrains Viral Escape.
.
Cell Host Microbe. 22(3):343-353.e3.
Patnaik A
,
Swanson KD
,
Csizmadia E
,
Solanki A
,
Landon-Brace N
,
Gehring MP
,
Helenius K
,
Olson BM
,
Pyzer AR
,
Wang LC
et al.
. 2017.
Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity.
.
Cancer Discov. 7(7):750-765.
Huang L
,
Fernandes H
,
Zia H
,
Tavassoli P
,
Rennert H
,
Pisapia D
,
Imielinski M
,
Sboner A
,
Rubin MA
,
Kluk M
et al.
. 2017.
The cancer precision medicine knowledge base for structured clinical-grade mutations and interpretations.
.
J Am Med Inform Assoc. 24(3):513-519.
Prabhu VV
,
Lulla AR
,
Madhukar NS
,
Ralff MD
,
Zhao D
,
Kline CLeah B
,
A Van den Heuvel PJ
,
Lev A
,
Garnett MJ
,
McDermott U
et al.
. 2017.
Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.
.
PLoS One. 12(8):e0180541.
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