Publications

Xu C, Us I, Cohen-Setton J, Milo M, Sidders B, Fitzgibbon J, Melnick AM, Pan H, Elemento O, Bulusu KC.  2024.  PAIRWISE: Deep Learning-based Prediction of Effective Personalized Drug Combinations in Cancer.. bioRxiv.

Duan X, Zhang T, Feng L, de Silva N, Greenspun B, Wang X, Moyer J, M Martin L, Chandwani R, Elemento O et al..  2024.  A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS.. Cell Stem Cell. 31(1):71-88.e8.

Rowdo FPMadorsky, Xiao G, Khramtsova GF, Nguyen J, Martini R, Stonaker B, Boateng R, Oppong JK, Adjei EK, Awuah B et al..  2024.  Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment.. Cancer Lett. 584:216608.

Glass J, Elemento O.  2024.  The power and perils of large language models in haematology.. Br J Haematol. 205(6):2190-2192.

Manzo OL, Nour J, Sasset L, Marino A, Rubinelli L, Palikhe S, Smimmo M, Hu Y, Bucci MRosaria, Borczuk A et al..  2024.  Rewiring Endothelial Sphingolipid Metabolism to Favor S1P Over Ceramide Protects From Coronary Atherosclerosis.. Circ Res. 134(8):990-1005.

Altorki NK, Bhinder B, Borczuk AC, Elemento O, Mittal V, McGraw TE.  2024.  A signature of enhanced proliferation associated with response and survival to anti-PD-L1 therapy in early-stage non-small cell lung cancer.. Cell Rep Med. 5(3):101438.

Shah Y, Yang H, Mueller FB, Li C, Rahim SEGul, Varma E, Salinas T, Dadhania DM, Salvatore SP, Seshan SV et al..  2024.  Transcriptomic signatures of chronic active antibody-mediated rejection deciphered by RNA sequencing of human kidney allografts.. Kidney Int. 105(2):347-363.

Galletti G, Halima A, Gjyrezi A, Zhang J, Zimmerman B, Worroll D, Kallergi G, Barreja R, Ocean A, Saxena A et al..  2024.  Transferrin receptor-based circulating tumor cell enrichment provides a snapshot of the molecular landscape of solid tumors and correlates with clinical outcomes.. medRxiv.

Han X, Sui J, Nie K, Zhao Y, Lv X, Xie J, Tan L, Au-Yeung RKH, Ma J, Inghirami G et al..  2024.  Tumor evolution analysis uncovered immune-escape related mutations in relapse of diffuse large B-cell lymphoma.. Leukemia. 38(10):2276-2280.

Newman LA, Chen Y, Martini R, Demaria S, Formenti S, Elemento O, Davis MB.  2024.  Tumor-Associated Lymphocytes and Breast Cancer Survival in Black and White Women.. JAMA Surg. 159(6):712-714.

Bensoussan Y, Elemento O, Rameau A.  2024.  Voice as an AI Biomarker of Health-Introducing Audiomics.. JAMA Otolaryngol Head Neck Surg. 150(4):283-284.

Lukose G, Assaad MAl, Driskill JH, Levine MF, Gundem G, Semaan A, Wilkes DC, Spigland NA, Medina-Martínez JS, Sboner A et al..  2024.  Whole genome profiling of rare pediatric thoracic tumors elucidates a YAP1::LEUTX fusion in an unclassified biphasic embryonal neoplasm.. Pathol Res Pract. 264:155726.

Stephan C, Assaad MAl, Levine MF, Deshpande A, Sigouros M, Manohar J, Sboner A, Elemento O, Pavlick AC, Mosquera JMiguel.  2024.  Whole genome sequencing elucidates etiological differences in MCPyV-negative Merkel cell carcinoma.. Pathol Res Pract. 263:155668.

Assaad MAl, Michaud O, Semaan A, Sigouros M, Tranquille M, Phan A, Levine MF, Gundem G, Medina-Martínez JS, Papaemmanuil E et al..  2024.  Whole-Genome Sequencing Analysis of Male Breast Cancer Unveils Novel Structural Events and Potential Therapeutic Targets.. Mod Pathol. 37(4):100452.

Johnson M, Bell A, Lauing KL, Ladomersky E, Zhai L, Penco-Campillo M, Shah Y, Mauer E, Xiu J, Nicolaides T et al..  2023.  Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence.. Clin Cancer Res. 29(23):4973-4989.

Johnson JL, Yaron TM, Huntsman EM, Kerelsky A, Song J, Regev A, Lin T-Y, Liberatore K, Cizin DM, Cohen BM et al..  2023.  An atlas of substrate specificities for the human serine/threonine kinome.. Nature. 613(7945):759-766.

Khani F, Hooper WF, Wang X, Chu TR, Shah M, Winterkorn L, Sigouros M, Conteduca V, Pisapia D, Wobker S et al..  2023.  Author Correction: Evolution of structural rearrangements in prostate cancer intracranial metastases.. NPJ Precis Oncol. 7(1):113.

Rajendran S, Brendel M, Barnes J, Zhan Q, Malmsten JE, Zisimopoulos P, Sigaras A, Ofori-Atta K, Meseguer M, Miller KA et al..  2023.  Automatic Ploidy Prediction and Quality Assessment of Human Blastocyst Using Time-Lapse Imaging.. bioRxiv.

Choi S, Whitman MA, Shimpi AA, Sempertegui ND, Chiou AE, Druso JE, Verma A, Lux SC, Cheng Z, Paszek M et al..  2023.  Bone-matrix mineralization dampens integrin-mediated mechanosignalling and metastatic progression in breast cancer.. Nat Biomed Eng. 7(11):1455-1472.

Liu S, Benito-Martin A, Vatter FAPelissie, Hanif SZ, Liu C, Bhardwaj P, Sethupathy P, Farghli AR, Piloco P, Paik P et al..  2023.  Breast adipose tissue-derived extracellular vesicles from obese women alter tumor cell metabolism.. EMBO Rep. 24(12):e57339.

Liu S, Benito-Martin A, Vatter FAPelissie, Hanif SZ, Liu C, Bhardwaj P, Sethupathy P, Farghli AR, Piloco P, Paik P et al..  2023.  Breast adipose tissue-derived extracellular vesicles from women with obesity stimulate mitochondrial-induced dysregulated tumor cell metabolism.. bioRxiv.

Shah SB, Carlson CR, Lai K, Zhong Z, Marsico G, Lee KM, Vélez NEFélix, Abeles EB, Allam M, Hu T et al..  2023.  Combinatorial treatment rescues tumour-microenvironment-mediated attenuation of MALT1 inhibitors in B-cell lymphomas.. Nat Mater. 22(4):511-523.

Huang SH, Sartorello G, Shen P-T, Xu C, Elemento O, Shvets G.  2023.  Correction: Metasurface-enhanced infrared spectroscopy in multiwell format for real-time assaying of live cells.. Lab Chip. 23(17):3893.

Liu W, Newhall KP, Khani F, Barlow LM, Nguyen D, Gu L, Eng K, Bhinder B, Uppal M, Récapet C et al..  2023.  The Cytidine Deaminase APOBEC3G Contributes to Cancer Mutagenesis and Clonal Evolution in Bladder Cancer.. Cancer Res. 83(4):506-520.

Assaad MAl, Shin N, Sigouros M, Manohar J, Antysheva Z, Kotlov N, Kiriy D, Nikitina A, Kleimenov M, Tsareva A et al..  2023.  Deciphering the origin and therapeutic targets of cancer of unknown primary: a case report that illustrates the power of integrative whole-exome and transcriptome sequencing analysis.. Front Oncol. 13:1274163.