Elemento Lab

Publications

Found 497 results

2025

Rowdo FPMadorsky, Martini R, Ackermann SE, Tang CP, Tranquille M, Irizarry A, Us I, Alawa O, Moyer JE, Sigouros M et al.. 2025. Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition.. Cancer Res. 85(3):551-566.

He Y, Waltman P, Kane T, Sigouros M, Chandra P, Gorski K, Zhang C, Proietti A, Singh A, Mittal V et al.. 2025. Longitudinal Genomic Analysis of Five Cases of Recurrent Thymomas.. J Thorac Oncol.

Guevara D, Shin N, Boiko A, Valiev I, Elsaeed AG, Mosquera JMiguel, Assaad MAl, Manohar J, Sigouros M, Zaichikova A et al.. 2025. Mesonephric Adenocarcinoma in a Young Male Patient.. Anticancer Res. 45(2):619-623.

Chen HJoyce, Gardner EE, Shah Y, Zhang K, Thakur A, Zhang C, Elemento O, Varmus H. 2025. Metastatic small cell lung cancer arises from TP53/RB1-deficient and MYC overproduction hESC-derived PNECs.. Elife. 13

Vicario R, Fragkogianni S, Weber L, Lazarov T, Hu Y, Hayashi SY, Craddock B, Socci ND, Alberdi A, Baako A et al.. 2025. A microglia clonal inflammatory disorder in Alzheimer's disease.. Elife. 13

Ruan J, Bond DA, Shah BD, Allan JN, Rutherford SC, Gribbin C, Chen Z, Bhinder B, Tam W, Rossi D et al.. 2025. MRD-driven Initial Therapy of Acalabrutinib and Lenalidomide plus Rituximab (ALR) or Obinutuzumab (ALO) for Mantle Cell Lymphoma.. Blood Adv.

de la Mora JDelgado-, Assaad MAl, Quitian S, Levine MF, Deshpande A, Sigouros M, Manohar J, Medina-Martínez JS, Sboner A, Elemento O et al.. 2025. Novel structural variants that impact cell cycle genes are elucidated in metastatic gastrointestinal stromal tumors.. Pathol Res Pract. 266:155782.

Kyei I, Bea VJ, Gyan KK, Adjei E, Stonaker B, Bekele M, Abebe E, Davis M, Boakye A, Boateng R et al.. 2025. Oncologic Anthropology and the African Diaspora: Twenty-Year Anniversary Report, International Center for the Study of Breast Cancer Subtypes (ICSBCS).. Ann Surg Oncol.

Hanif SZ, Au CMCherie, Torregroza I, Kutz C, Jannath SY, Fabiha T, Bhinder B, Washburn MP, Devost D, Liu S et al.. 2025. The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization.. bioRxiv.

Cheng APellan, Rusinek I, Sossin A, Widman AJ, Meiri E, Krieger G, Hirschberg O, Tov DShem, Gilad S, Jaimovich A et al.. 2025. Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules.. bioRxiv.

Bhinder B, Friedl V, Sethuraman S, Risso D, Chiotti KE, R Mashl J, Ellrott KP, Lee JA, Wong CK, Gyan K et al.. 2025. Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles.. Sci Rep. 15(1):23921.

Fiore D, Cappelli LVincenzo, Zhaoqi L, Kotlov N, Sorokina M, Phillip J, Zumbo P, Yoffe L, Ghione P, Wang A et al.. 2025. A patient-derived T cell lymphoma biorepository uncovers pathogenetic mechanisms and host-related therapeutic vulnerabilities.. Cell Rep Med. 6(4):102029.

K Devi SP, Wang E, Jaiswal A, Konieczny P, Kim T-G, Nirschl CJ, Verma A, Liu Y, Milczanowski J, Christo SN et al.. 2025. PD-1 is requisite for skin T cell formation and specification by TGFβ.. Nat Immunol. 26(8):1339-1351.

Bai Z, Osman M, Brendel M, Tangen CM, Flaig TW, Thompson IM, Plets M, M Lucia S, Theodorescu D, Gustafson D et al.. 2025. Predicting response to neoadjuvant chemotherapy in muscle-invasive bladder cancer via interpretable multimodal deep learning.. NPJ Digit Med. 8(1):174.

Bayou N, Henretta S, Munoz-Arcos L, Molteni E, Gianni C, Serafini MSerena, Nicolò E, Pontolillo L, Pasto B, Gaudio HAndrew et al.. 2025. Quantitative HER2 profiling on circulating tumor cells using an EpCAM-independent platform in metastatic breast cancer.. Cancer Cell Int. 25(1):439.

Akinsanya K, AlQuraishi M, Boija A, Chodera J, Cichońska A, Ghassemi M, Head M, Jin W, Kibbe WA, Krogan N et al.. 2025. Redefining druggable targets with artificial intelligence.. Nat Biotechnol. 43(9):1416-1418.

Vicario R, Fragkogianni S, Pokrovskii M, Meyer C, Lopez-Rodrigo E, Hu Y, Ogishi M, Alberdi A, Baako A, Ay O et al.. 2025. Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration.. Neuron. 113(7):1065-1081.e13.

Kim J, Ravichandran H, Yoffe L, Bhinder B, Finos K, Singh A, Pua BB, Bates S, Huang BEmma, Rendeiro AF et al.. 2025. Simultaneous immunomodulation and epithelial-to-mesenchymal transition drives lung adenocarcinoma progression.. bioRxiv.

Park J, De Gregorio R, Hissong E, Ozcelik E, Bartelo N, Dezem FSegato, Zhang L, Marção M, Chasteen H, Zheng Y et al.. 2025. The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs.. bioRxiv.

Rubinelli L, Manzo OLaura, Sungho J, Del Gaudio I, Bareja R, Marino A, Palikhe S, Di Mauro V, Bucci M, Falcone DJ et al.. 2025. Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases.. Nat Commun. 16(1):1968.

Ovejero S, Devin J, Alibert L, Soun C, Lin Y-L, Dutrieux L, Abouladze M, de Paco EGarcia, Gadacha OKarmous, Constantinou A et al.. 2025. Synthetic Lethal Combinations of DNA Repair Inhibitors and Genotoxic Agents to Target High-Risk Diffuse Large B Cell Lymphoma.. Hematol Oncol. 43(5):e70131.

Roshal M, Kong IY, Dinalankara W, Reichel JB, Teater M, Binder B, Zairis S, Brody JD, Park SI, Kovach AE et al.. 2025. Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein response.. bioRxiv.

Honigsberg R, Cruz T, Yoffe L, Tang MStephanie, Dicle O, Markowitz G, Michael M, Singh A, Altorki NK, Elemento O et al.. 2025. Tumor-specific draining lymph node CD8 T cells orchestrate an anti-tumor response to neoadjuvant PD-1 immune checkpoint blockade.. bioRxiv.

Nath S, Claridge S, Granados GLara, Assaad MAl, Park E, Cavallo J-A, Nuwere U, Ackon MEsi, De Boni L, Baker S et al.. 2025. Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer.. Cell Rep Med. 6(7):102218.

Guevara D, Shin N, Boiko A, Valiev I, Elsaeed AG, Mosquera JMiguel, Assaad MAl, Manohar J, Sigouros M, Zaichikova A et al.. 2025. Unusual Presentation of Advanced Urothelial Cancer in a Young Patient.. Anticancer Res. 45(2):613-618.