Publications

Cuppen E, Elemento O, Rosenquist R, Nikic S, IJzerman M, Zaleski IDurand, Frederix G, Levin L-Å, Mullighan CG, Buettner R et al..  2022.  Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care.. JCO Precis Oncol. 6:e2200245.

Argueta LB, Lacko LA, Bram Y, Tada T, Carrau L, Rendeiro AFigueiredo, Zhang T, Uhl S, Lubor BC, Chandar V et al..  2022.  Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy.. iScience. 25(5):104223.

Raman R, Villefranc JA, Ullmann TM, Thiesmeyer J, Anelli V, Yao J, Hurley JR, Pauli C, Bareja R, Eng KWha et al..  2022.  Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer.. J Exp Med. 219(6)

He Y, Kim I-K, Bian J, Polyzos A, Di Giammartino DCampigli, Zhang Y-W, Luo J, Hernandez MO, Kedei N, Cam M et al..  2022.  A Knock-In Mouse Model of Thymoma With the GTF2I L424H Mutation.. J Thorac Oncol. 17(12):1375-1386.

Linares JF, Cid-Diaz T, Duran A, Osrodek M, Martinez-Ordoñez A, Reina-Campos M, Kuo H-H, Elemento O, M Martin L, Cordes T et al..  2022.  The lactate-NAD axis activates cancer-associated fibroblasts by downregulating p62.. Cell Rep. 39(6):110792.

Greenberg J, Limberg J, Verma A, Kim D, Chen X, Lee YJ, Moore MD, Ullmann TM, Thiesmeyer JW, Loewenstein Z et al..  2022.  Metastatic pancreatic neuroendocrine tumors feature elevated T cell infiltration.. JCI Insight. 7(23)

Ertl IE, Lemberger U, Ilijazi D, Hassler MR, Bruchbacher A, Brettner R, Kronabitter H, Gutmann M, Vician P, Zeitler G et al..  2022.  Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound.. Eur Urol. 82(3):261-270.

Matrai CE, Ohara K, Eng KWha, Glynn SM, Chandra P, Chatterjee-Paer S, Motanagh S, Mirabelli S, Kurtis B, He B et al..  2022.  Molecular Evaluation of Low-grade Low-stage Endometrial Cancer With and Without Recurrence.. Int J Gynecol Pathol. 41(3):207-219.

Podaza E, Kuo H-H, Nguyen J, Elemento O, M Martin L.  2022.  Next generation patient derived tumor organoids.. Transl Res. 250:84-97.

Hu Y, Bloy N, Elemento O, Buqué A.  2022.  Nicotinamide drives T cell activation in the mammary tumor microenvironment.. J Transl Med. 20(1):251.

Drozdz MM, Doane AS, Alkallas R, Desman G, Bareja R, Reilly M, Bang J, Yusupova M, You J, Eraslan Z et al..  2022.  A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation.. Cell Rep. 40(13):111412.

Rendeiro AF, Ravichandran H, Kim J, Borczuk AC, Elemento O, Schwartz RE.  2022.  Persistent alveolar type 2 dysfunction and lung structural derangement in post-acute COVID-19.. medRxiv.

Ullmann TM, Thiesmeyer JW, Lee YJoo, Beg S, Mosquera JMiguel, Elemento O, Fahey TJ, Scognamiglio T, Houvras Y.  2022.  RET Fusion-Positive Papillary Thyroid Cancers are Associated with a More Aggressive Phenotype.. Ann Surg Oncol.

Laurent P, Yang C, Rendeiro AF, Nilsson-Payant BE, Carrau L, Chandar V, Bram Y, tenOever BR, Elemento O, Ivashkiv LB et al..  2022.  Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19.. Sci Immunol. 7(75):eadd4906.

Shohdy KS, Villamar DM, Cao Y, Trieu J, Price KS, Nagy R, Tagawa ST, Molina AM, Sternberg CN, Nanus DM et al..  2022.  Serial ctDNA analysis predicts clinical progression in patients with advanced urothelial carcinoma.. Br J Cancer. 126(3):430-439.

Kulm S, Kofman L, Mezey J, Elemento O.  2022.  Simple Linear Cancer Risk Prediction Models With Novel Features Outperform Complex Approaches.. JCO Clin Cancer Inform. 6:e2100166.

Park J, Kim J, Lewy T, Rice CM, Elemento O, Rendeiro AF, Mason CE.  2022.  Spatial omics technologies at multimodal and single cell/subcellular level.. Genome Biol. 23(1):256.

Park J, Foox J, Hether T, Danko DC, Warren S, Kim Y, Reeves J, Butler DJ, Mozsary C, Rosiene J et al..  2022.  System-wide transcriptome damage and tissue identity loss in COVID-19 patients.. Cell Rep Med. 3(2):100522.

Alnajar H, Ravichandran H, Rendeiro AFigueiredo, Ohara K, Zoughbi WAl, Manohar J, Greco N, Sigouros M, Fox J, Muth E et al..  2022.  Tumor-immune microenvironment revealed by Imaging Mass Cytometry in a metastatic sarcomatoid urothelial carcinoma with a prolonged response to pembrolizumab.. Cold Spring Harb Mol Case Stud. 8(3)

Schad SE, Chow A, Mangarin L, Pan H, Zhang J, Ceglia N, Caushi JX, Malandro N, Zappasodi R, Gigoux M et al..  2022.  Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions.. J Exp Med. 219(6)

Yu H, Sfakianos JP, Wang L, Hu Y, Daza J, Galsky MD, Sandhu HS, Elemento O, Faltas BM, Farkas AM et al..  2022.  Tumor-Infiltrating Myeloid Cells Confer De Novo Resistance to PD-L1 Blockade through EMT-Stromal and Tgfβ-Dependent Mechanisms.. Mol Cancer Ther. 21(11):1729-1741.

Kim J, Rustam S, Mosquera JMiguel, Randell SH, Shaykhiev R, Rendeiro AF, Elemento O.  2022.  Unsupervised discovery of tissue architecture in multiplexed imaging.. Nat Methods. 19(12):1653-1661.

Rajappa P, Eng KW, Bareja R, Bander ED, Yuan M, Dua A, Maachani UBhanu, Snuderl M, Pan H, Zhang T et al..  2022.  Utility of multimodality molecular profiling for pediatric patients with central nervous system tumors.. Neurooncol Adv. 4(1):vdac031.

Brendel M, Getseva V, Assaad MAl, Sigouros M, Sigaras A, Kane T, Khosravi P, Mosquera JMiguel, Elemento O, Hajirasouliha I.  2022.  Weakly-supervised tumor purity prediction from frozen H&E stained slides.. EBioMedicine. 80:104067.

Cyrta J, Rosiene J, Bareja R, Kudman S, Zoughbi WAl, Motanagh S, Wilkes DC, Eng K, Zhang T, Sticca E et al..  2022.  Whole-genome characterization of myoepithelial carcinomas of the soft tissue.. Cold Spring Harb Mol Case Stud. 8(7)