Elemento Lab

Publications

Found 408 results

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2026

Assaad MAl, Hadi K, Levine MF, Guevara D, Patel M, Tranquille M, King A, Otilano J, Semaan A, Gundem G et al.. 2026. Whole genome sequencing approach to assess homologous recombination deficiency in a pan-cancer cohort.. Commun Med (Lond). 6(1):5.

Kozan ENur, de la Mora JDelgado-, Assaad MAl, Ginter P, Gundem G, Levine MF, Gorski K, Phan A, Beg S, Sigaras A et al.. 2026. Whole genome sequencing of locally advanced and metastatic breast carcinoma unravels relevant molecular signatures and novel events.. Pathol Res Pract. 282:156469.

2025

Yoffe L, Bhinder B, Kang SWook, Zhang H, Singh A, Ravichandran H, Markowitz G, Martin M, Kim J, Zhang C et al.. 2025. Acquisition of discrete immune suppressive barriers contributes to the initiation and progression of preinvasive to invasive human lung cancer.. bioRxiv.

Yoffe L, Bhinder B, Kang SWook, Zhang H, Singh A, Ravichandran H, Markowitz G, Martin M, Kim J, Zhang C et al.. 2025. Acquisition of discrete immune suppressive barriers contributes to the initiation and progression of preinvasive to invasive human lung cancer.. bioRxiv.

de la Mora JDelgado-, Assaad MAl, Karaaslan S, Hadi K, Halima A, Deshpande A, Manohar J, Sigouros M, Medina-Martínez JS, Lieberman MD et al.. 2025. Corrigendum to "Whole genome and transcriptome analysis of pancreatic acinar cell carcinoma elucidates mechanisms of homologous recombination deficiency and unravels novel relevant fusion events" [Pathol. - Res. Pract. 266 (2025) 155798].. Pathol Res Pract. 266:155825.

Kim YE, Dobko M, Li H, Shao T, Periyakoil P, Tipton C, Colasacco C, Serpedin A, Elemento O, Sabuncu M et al.. 2025. A Deep-Learning Model for Multi-class Audio Classification of Vocal Fold Pathologies in Office Stroboscopy.. Laryngoscope. 135(7):2428-2436.

Cheng APellan, Widman AJ, Arora A, Rusinek I, Sossin A, Rajagopalan S, Midler N, Hooper WF, Murray RM, Halmos D et al.. 2025. Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling.. Nat Methods. 22(5):973-981.

Phipps W, Bhinder B, Towlerton A, Mooka P, Kafeero J, Fitzgibbon M, Elemento O, Cesarman E. 2025. Exome Sequencing Reveals a Sparse Genomic Landscape in Kaposi Sarcoma.. Mol Cancer Res. 23(5):438-449.

Claridge SE, Nath S, Baum A, Farias R, Cavallo J-A, Rizvi NM, De Boni L, Park E, Granados GLara, Hauesgen M et al.. 2025. Functional genomics pipeline identifies CRL4 inhibition for the treatment of ovarian cancer.. Clin Transl Med. 15(2):e70078.

Claridge SE, Nath S, Baum A, Farias R, Cavallo J-A, Rizvi NM, De Boni L, Park E, Granados GLara, Hauesgen M et al.. 2025. Functional genomics pipeline identifies CRL4 inhibition for the treatment of ovarian cancer.. Clin Transl Med. 15(2):e70078.

Ranti D, Yu H, Salomé B, Bang S, Duquesne I, Wang YA, Bieber C, Strandgaard T, Merritt E, Doherty G et al.. 2025. HLA-E and NKG2A Mediate Resistance to BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer.. bioRxiv.

Ranti D, Yu H, Salomé B, Bang S, Duquesne I, Wang YA, Bieber C, Strandgaard T, Merritt E, Doherty G et al.. 2025. HLA-E and NKG2A Mediate Resistance to BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer.. bioRxiv.

Ranti D, Yu H, Salomé B, Bang S, Duquesne I, Wang YA, Bieber C, Strandgaard T, Merritt E, Doherty G et al.. 2025. HLA-E and NKG2A Mediate Resistance to BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer.. bioRxiv.

Ranti D, Yu H, Salomé B, Bang S, Duquesne I, Wang YA, Bieber C, Strandgaard T, Merritt E, Doherty G et al.. 2025. HLA-E and NKG2A Mediate Resistance to BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer.. bioRxiv.

Hissong E, Bhinder B, Kim J, Ohara K, Ravichandran H, Assaad MAl, Elsoukkary S, Shusterman M, Khan U, Eng KWha et al.. 2025. Integrative transcriptomic and single-cell protein characterization of colorectal carcinoma delineates distinct tumor immune microenvironments associated with overall survival.. Pathol Res Pract. 273:156150.

Hissong E, Bhinder B, Kim J, Ohara K, Ravichandran H, Assaad MAl, Elsoukkary S, Shusterman M, Khan U, Eng KWha et al.. 2025. Integrative transcriptomic and single-cell protein characterization of colorectal carcinoma delineates distinct tumor immune microenvironments associated with overall survival.. Pathol Res Pract. 273:156150.

Barton BM, Son F, Verma A, Bal SKumar, Tang Q, Wang R, Umphred-Wilson K, Khan R, Trichka J, Dong H et al.. 2025. IRE1α-XBP1 safeguards hematopoietic stem and progenitor cells by restricting pro-leukemogenic gene programs.. Nat Immunol. 26(2):200-214.

Rowdo FPMadorsky, Martini R, Ackermann SE, Tang CP, Tranquille M, Irizarry A, Us I, Alawa O, Moyer JE, Sigouros M et al.. 2025. Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition.. Cancer Res. 85(3):551-566.

He Y, Waltman P, Kane T, Sigouros M, Chandra P, Gorski K, Zhang C, Proietti A, Singh A, Mittal V et al.. 2025. Longitudinal Genomic Analysis of Five Cases of Recurrent Thymomas.. J Thorac Oncol.

Vicario R, Fragkogianni S, Weber L, Lazarov T, Hu Y, Hayashi SY, Craddock B, Socci ND, Alberdi A, Baako A et al.. 2025. A microglia clonal inflammatory disorder in Alzheimer's disease.. Elife. 13

Kyei I, Bea VJ, Gyan KK, Adjei E, Stonaker B, Bekele M, Abebe E, Davis M, Boakye A, Boateng R et al.. 2025. Oncologic Anthropology and the African Diaspora: Twenty-Year Anniversary Report, International Center for the Study of Breast Cancer Subtypes (ICSBCS).. Ann Surg Oncol.

Kyei I, Bea VJ, Gyan KK, Adjei E, Stonaker B, Bekele M, Abebe E, Davis M, Boakye A, Boateng R et al.. 2025. Oncologic Anthropology and the African Diaspora: Twenty-Year Anniversary Report, International Center for the Study of Breast Cancer Subtypes (ICSBCS).. Ann Surg Oncol.

Kyei I, Bea VJ, Gyan KK, Adjei E, Stonaker B, Bekele M, Abebe E, Davis M, Boakye A, Boateng R et al.. 2025. Oncologic Anthropology and the African Diaspora: Twenty-Year Anniversary Report, International Center for the Study of Breast Cancer Subtypes (ICSBCS).. Ann Surg Oncol.

Hanif SZ, Au CMCherie, Torregroza I, Kutz C, Jannath SY, Fabiha T, Bhinder B, Washburn MP, Devost D, Liu S et al.. 2025. The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization.. bioRxiv.

Cheng APellan, Rusinek I, Sossin A, Widman AJ, Meiri E, Krieger G, Hirschberg O, Tov DShem, Gilad S, Jaimovich A et al.. 2025. Paired plus-minus sequencing is an ultra-high throughput and accurate method for dual strand sequencing of DNA molecules.. bioRxiv.