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Found 301 results
Author
Title
Type
Year
Journal Article
Rennert H
,
Eng K
,
Zhang T
,
Tan A
,
Xiang J
,
Romanel A
,
Kim R
,
Tam W
,
Liu Y-C
,
Bhinder B
et al.
. 2016.
Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care.
.
NPJ Genom Med. 1
Elemento O
. 2007.
Developing a systems-level understanding of gene expression.
.
Genome Biol. 8(4):304.
Marderstein AR
,
Uppal M
,
Verma A
,
Bhinder B
,
Tayyebi Z
,
Mezey J
,
Clark AG
,
Elemento O
. 2020.
Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues.
.
Nat Commun. 11(1):2213.
Puca L
,
Gavyert K
,
Sailer V
,
Conteduca V
,
Dardenne E
,
Sigouros M
,
Isse K
,
Kearney M
,
Vosoughi A
,
Fernandez L
et al.
. 2019.
Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer.
.
Sci Transl Med. 11(484)
Rickman KA
,
Lach FP
,
Abhyankar A
,
Donovan FX
,
Sanborn EM
,
Kennedy JA
,
Sougnez C
,
Gabriel SB
,
Elemento O
,
Chandrasekharappa SC
et al.
. 2015.
Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia.
.
Cell Rep. 12(1):35-41.
Jiang Y
,
Redmond D
,
Nie K
,
Eng KW
,
Clozel T
,
Martin P
,
Tan LHc
,
Melnick AM
,
Tam W
,
Elemento O
. 2014.
Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas.
.
Genome Biol. 15(8):432.
Page DB
,
Yuan J
,
Redmond D
,
Y Wen H
,
Durack JC
,
Emerson R
,
Solomon S
,
Dong Z
,
Wong P
,
Comstock C
et al.
. 2016.
Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy.
.
Cancer Immunol Res. 4(10):835-844.
Courtiol P
,
Maussion C
,
Moarii M
,
Pronier E
,
Pilcer S
,
Sefta M
,
Manceron P
,
Toldo S
,
Zaslavskiy M
,
Le Stang N
et al.
. 2019.
Deep learning-based classification of mesothelioma improves prediction of patient outcome.
.
Nat Med. 25(10):1519-1525.
Xu Z
,
Verma A
,
Naveed U
,
Bakhoum SF
,
Khosravi P
,
Elemento O
. 2021.
Deep learning predicts chromosomal instability from histopathology images.
.
iScience. 24(5):102394.
Khosravi P
,
Kazemi E
,
Zhan Q
,
Malmsten JE
,
Toschi M
,
Zisimopoulos P
,
Sigaras A
,
Lavery S
,
Cooper LAD
,
Hickman C
et al.
. 2019.
Deep learning enables robust assessment and selection of human blastocysts after in vitro fertilization.
.
NPJ Digit Med. 2:21.
Khosravi P
,
Lysandrou M
,
Eljalby M
,
Li Q
,
Kazemi E
,
Zisimopoulos P
,
Sigaras A
,
Brendel M
,
Barnes J
,
Ricketts C
et al.
. 2021.
A Deep Learning Approach to Diagnostic Classification of Prostate Cancer Using Pathology-Radiology Fusion.
.
J Magn Reson Imaging. 54(2):462-471.
Khosravi P
,
Kazemi E
,
Imielinski M
,
Elemento O
,
Hajirasouliha I
. 2018.
Deep Convolutional Neural Networks Enable Discrimination of Heterogeneous Digital Pathology Images.
.
EBioMedicine. 27:317-328.
Gayvert KM
,
Madhukar NS
,
Elemento O
. 2016.
A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials.
.
Cell Chem Biol. 23(10):1294-1301.
Jiang Y
,
Ortega-Molina A
,
Geng H
,
Ying H-Y
,
Hatzi K
,
Parsa S
,
McNally D
,
Wang L
,
Doane AS
,
Agirre X
et al.
. 2017.
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.
.
Cancer Discov. 7(1):38-53.
Lu X
,
Li JM
,
Elemento O
,
Tavazoie S
,
Wieschaus EF
. 2009.
Coupling of zygotic transcription to mitotic control at the Drosophila mid-blastula transition.
.
Development. 136(12):2101-10.
Lis R
,
Karrasch CC
,
Poulos MG
,
Kunar B
,
Redmond D
,
Duran JGBarcia
,
Badwe CR
,
Schachterle W
,
Ginsberg M
,
Xiang J
et al.
. 2017.
Conversion of adult endothelium to immunocompetent haematopoietic stem cells.
.
Nature. 545(7655):439-445.
Gollamudi S
,
Johri A
,
Calingasan NY
,
Yang L
,
Elemento O
,
M Beal F
. 2012.
Concordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human Parkinson's disease.
.
PLoS One. 7(5):e36191.
Benedicto I
,
Lehmann GL
,
Ginsberg M
,
Nolan DJ
,
Bareja R
,
Elemento O
,
Salfati Z
,
Alam NM
,
Prusky GT
,
Llanos P
et al.
. 2017.
Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors.
.
Nat Commun. 8:15374.
Bhinder B
,
Elemento O
. 2020.
Computational methods in tumor immunology.
.
Methods Enzymol. 636:209-259.
Gayvert KM
,
Dardenne E
,
Cheung C
,
Boland MRegina
,
Lorberbaum T
,
Wanjala J
,
Chen Y
,
Rubin MA
,
Tatonetti NP
,
Rickman DS
et al.
. 2016.
A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors.
.
Cell Rep. 15(11):2348-56.
Gayvert KM
,
Aly O
,
Platt J
,
Bosenberg MW
,
Stern DF
,
Elemento O
. 2017.
A Computational Approach for Identifying Synergistic Drug Combinations.
.
PLoS Comput Biol. 13(1):e1005308.
Vikova V
,
Jourdan M
,
Robert N
,
Requirand G
,
Boireau S
,
Bruyer A
,
Vincent L
,
Cartron G
,
Klein B
,
Elemento O
et al.
. 2019.
Comprehensive characterization of the mutational landscape in multiple myeloma cell lines reveals potential drivers and pathways associated with tumor progression and drug resistance.
.
Theranostics. 9(2):540-553.
Meyer KD
,
Saletore Y
,
Zumbo P
,
Elemento O
,
Mason CE
,
Jaffrey SR
. 2012.
Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons.
.
Cell. 149(7):1635-46.
Vosoughi A
,
Zhang T
,
Shohdy KS
,
Vlachostergios PJ
,
Wilkes DC
,
Bhinder B
,
Tagawa ST
,
Nanus DM
,
Molina AM
,
Beltran H
et al.
. 2020.
Common germline-somatic variant interactions in advanced urothelial cancer.
.
Nat Commun. 11(1):6195.
Culjkovic-Kraljacic B
,
Fernando TM
,
Marullo R
,
Calvo-Vidal N
,
Verma A
,
Yang SN
,
Tabbò F
,
Gaudiano M
,
Zahreddine H
,
Goldstein RL
et al.
. 2016.
Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas.
.
Blood. 127(7):858-68.
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