Publications

Doane AS, Elemento O.  2017.  Regulatory elements in molecular networks.. Wiley Interdiscip Rev Syst Biol Med. 9(3)

Mauer J, Luo X, Blanjoie A, Jiao X, Grozhik AV, Patil DP, Linder B, Pickering BF, Vasseur J-J, Chen Q et al..  2017.  Reversible methylation of mA in the 5' cap controls mRNA stability.. Nature. 541(7637):371-375.

Dave B, Gonzalez DD, Bin Liu Z-, Li X, Wong H, Granados S, Ezzedine NE, Sieglaff DH, Ensor JE, Miller KD et al..  2017.  Role of RPL39 in Metaplastic Breast Cancer.. J Natl Cancer Inst. 109(6)

Han T, Schatoff EM, Murphy C, Zafra MPaz, Wilkinson JE, Elemento O, Dow LE.  2017.  R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine.. Nat Commun. 8:15945.

Poran A, Nötzel C, Aly O, Mencia-Trinchant N, Harris CT, Guzman ML, Hassane DC, Elemento O, Kafsack BFC.  2017.  Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites.. Nature. 551(7678):95-99.

Schachterle W, Badwe CR, Palikuqi B, Kunar B, Ginsberg M, Lis R, Yokoyama M, Elemento O, Scandura JM, Rafii S.  2017.  Sox17 drives functional engraftment of endothelium converted from non-vascular cells.. Nat Commun. 8:13963.

Ge Y, Gomez NC, Adam RC, Nikolova M, Yang H, Verma A, Lu CPei-Ju, Polak L, Yuan S, Elemento O et al..  2017.  Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.. Cell. 169(4):636-650.e14.

Giannopoulou E, Elemento O.  2017.  Systematic Discovery of Chromatin-Bound Protein Complexes from ChIP-seq Datasets.. Methods Mol Biol. 1507:43-58.

Nwachukwu JC, Srinivasan S, Bruno NE, Nowak J, Wright NJ, Minutolo F, Rangarajan ES, Izard T, Yao X-Q, Grant BJ et al..  2017.  Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.. Cell Chem Biol. 24(1):35-45.

Bhinder B, Elemento O.  2017.  Towards a better cancer precision medicine: systems biology meets immunotherapy.. Curr Opin Syst Biol. 2:67-73.

Liu Y, Pelham-Webb B, Di Giammartino DCampigli, Li J, Kim D, Kita K, Saiz N, Garg V, Doane A, Giannakakou P et al..  2017.  Widespread Mitotic Bookmarking by Histone Marks and Transcription Factors in Pluripotent Stem Cells.. Cell Rep. 19(7):1283-1293.

Faltas BM, Prandi D, Tagawa ST, Molina AM, Nanus DM, Sternberg C, Rosenberg J, Mosquera JMiguel, Robinson B, Elemento O et al..  2016.  Clonal evolution of chemotherapy-resistant urothelial carcinoma.. Nat Genet. 48(12):1490-1499.

Culjkovic-Kraljacic B, Fernando TM, Marullo R, Calvo-Vidal N, Verma A, Yang SN, Tabbò F, Gaudiano M, Zahreddine H, Goldstein RL et al..  2016.  Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas.. Blood. 127(7):858-68.

Gayvert KM, Dardenne E, Cheung C, Boland MRegina, Lorberbaum T, Wanjala J, Chen Y, Rubin MA, Tatonetti NP, Rickman DS et al..  2016.  A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors.. Cell Rep. 15(11):2348-56.

Gayvert KM, Madhukar NS, Elemento O.  2016.  A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials.. Cell Chem Biol. 23(10):1294-1301.

Page DB, Yuan J, Redmond D, Y Wen H, Durack JC, Emerson R, Solomon S, Dong Z, Wong P, Comstock C et al..  2016.  Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy.. Cancer Immunol Res. 4(10):835-844.

Rennert H, Eng K, Zhang T, Tan A, Xiang J, Romanel A, Kim R, Tam W, Liu Y-C, Bhinder B et al..  2016.  Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care.. NPJ Genom Med. 1

Allen JE, C Kline LB, Prabhu VV, Wagner J, Ishizawa J, Madhukar N, Lev A, Baumeister M, Zhou L, Lulla A et al..  2016.  Discovery and clinical introduction of first-in-class imipridone ONC201.. Oncotarget. 7(45):74380-74392.

Vazirani RP, Verma A, L Sadacca A, Buckman MS, Picatoste B, Beg M, Torsitano C, Bruno JH, Patel RT, Simonyte K et al..  2016.  Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance.. Diabetes. 65(6):1577-89.

Beltran H, Prandi D, Mosquera JMiguel, Benelli M, Puca L, Cyrta J, Marotz C, Giannopoulou E, Chakravarthi BVSK, Varambally S et al..  2016.  Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer.. Nat Med. 22(3):298-305.

Poulos MG, Ramalingam P, Gutkin MC, Kleppe M, Ginsberg M, Crowley MJP, Elemento O, Levine RL, Rafii S, Kitajewski J et al..  2016.  Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis.. Nat Commun. 7:13829.

Liu Y, Giannopoulou EG, Wen D, Falciatori I, Elemento O, C Allis D, Rafii S, Seandel M.  2016.  Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells.. Nat Commun. 7:11275.

Xylinas E, Hassler MR, Zhuang D, Krzywinski M, Erdem Z, Robinson BD, Elemento O, Clozel T, Shariat SF.  2016.  An Epigenomic Approach to Improving Response to Neoadjuvant Cisplatin Chemotherapy in Bladder Cancer.. Biomolecules. 6(3)

Béguelin W, Teater M, Gearhart MD, Fernández MTeresa Cal, Goldstein RL, Cárdenas MG, Hatzi K, Rosen M, Shen H, Corcoran CM et al..  2016.  EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.. Cancer Cell. 30(2):197-213.

Pritchard CC, Mateo J, Walsh MF, De Sarkar N, Abida W, Beltran H, Garofalo A, Gulati R, Carreira S, Eeles R et al..  2016.  Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.. N Engl J Med. 375(5):443-53.