Publications

Meyer KD, Patil DP, Zhou J, Zinoviev A, Skabkin MA, Elemento O, Pestova TV, Qian S-B, Jaffrey SR.  2015.  5' UTR m(6)A Promotes Cap-Independent Translation.. Cell. 163(4):999-1010.

Slonim N, Elemento O, Tavazoie S.  2006.  Ab initio genotype-phenotype association reveals intrinsic modularity in genetic networks.. Mol Syst Biol. 2:2006.0005.

Casiraghi N, Orlando F, Ciani Y, Xiang J, Sboner A, Elemento O, Attard G, Beltran H, Demichelis F, Romanel A.  2020.  ABEMUS: platform-specific and data-informed detection of somatic SNVs in cfDNA.. Bioinformatics. 36(9):2665-2674.

De S, Shaknovich R, Riester M, Elemento O, Geng H, Kormaksson M, Jiang Y, Woolcock B, Johnson N, Polo JM et al..  2013.  Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity.. PLoS Genet. 9(1):e1003137.

Halama A, Kulinski M, Dib SS, Zaghlool SB, Siveen KS, Iskandarani A, Zierer J, Prabhu KS, Satheesh NJ, Bhagwat AM et al..  2018.  Accelerated lipid catabolism and autophagy are cancer survival mechanisms under inhibited glutaminolysis.. Cancer Lett. 430:133-147.

González-González A, Muñoz-Muela E, Marchal JA, Cara FE, Molina MP, Cruz-Lozano M, Jiménez G, Verma A, Ramírez A, Qian W et al..  2018.  Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling.. Clin Cancer Res. 24(22):5697-5709.

Ginter PS, McIntire PJ, Kurtis B, Mirabelli S, Motanagh S, Hoda S, Elemento O, Shin SJ, Mosquera JMiguel.  2020.  Adenomyoepithelial tumors of the breast: molecular underpinnings of a rare entity.. Mod Pathol.

Teater M, Dominguez PM, Redmond D, Chen Z, Ennishi D, Scott DW, Cimmino L, Ghione P, Chaudhuri J, Gascoyne RD et al..  2018.  AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis.. Nat Commun. 9(1):222.

Kumar R, DiMenna L, Schrode N, Liu T-C, Franck P, Muñoz-Descalzo S, Hadjantonakis A-K, Zarrin AA, Chaudhuri J, Elemento O et al..  2013.  AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes.. Nature. 500(7460):89-92.

Israely E, Ginsberg M, Nolan D, Ding B-S, James D, Elemento O, Rafii S, Rabbany SY.  2014.  Akt suppression of TGFβ signaling contributes to the maintenance of vascular identity in embryonic stem cell-derived endothelial cells.. Stem Cells. 32(1):177-90.

Meggendorfer M, Jobanputra V, Wrzeszczynski KO, Roepman P, de Bruijn E, Cuppen E, Buttner R, Caldas C, Grimmond S, Mullighan CG et al..  2021.  Analytical demands to use whole-genome sequencing in precision oncology.. Semin Cancer Biol.

Pan H, Elemento O.  2018.  Analyzing DNA Methylation Patterns During Tumor Evolution.. Methods Mol Biol. 1711:27-53.

Chang S-H, Lu Y-C, Li X, Hsieh W-Y, Xiong Y, Ghosh M, Evans T, Elemento O, Hla T.  2013.  Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis.. J Biol Chem. 288(7):4908-21.

Glynn S, Lipkin S, Zhang T, Sboner A, Elemento O, van Besien K, Beltran H.  2019.  The application of precision medicine in diagnosing familial Mediterranean fever.. Leuk Lymphoma. 60(8):2091-2093.

Bhinder B, Gilvary C, Madhukar NS, Elemento O.  2021.  Artificial Intelligence in Cancer Research and Precision Medicine.. Cancer Discov. 11(4):900-915.

Elkhader J, Elemento O.  2021.  Artificial intelligence in oncology: From bench to clinic.. Semin Cancer Biol.

Zaninovic N, Elemento O, Rosenwaks Z.  2019.  Artificial intelligence: its applications in reproductive medicine and the assisted reproductive technologies.. Fertil Steril. 112(1):28-30.

Powles RL, Redmond D, Sotiriou C, Loi S, Fumagalli D, Nuciforo P, Harbeck N, de Azambuja E, Sarp S, Di Cosimo S et al..  2018.  Association of T-Cell Receptor Repertoire Use With Response to Combined Trastuzumab-Lapatinib Treatment of HER2-Positive Breast Cancer: Secondary Analysis of the NeoALTTO Randomized Clinical Trial.. JAMA Oncol. 4(11):e181564.

Woo XYi, Giordano J, Srivastava A, Zhao Z-M, Lloyd MW, de Bruijn R, Suh Y-S, Patidar R, Chen L, Scherer S et al..  2021.  Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.. Nat Genet. 53(5):761.

Verma N, Pan H, Doré LC, Shukla A, Li QV, Pelham-Webb B, Teijeiro V, González F, Krivtsov A, Chang C-J et al..  2018.  Author Correction: TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.. Nat Genet. 50(5):764.

Madhukar NS, Khade PK, Huang L, Gayvert K, Galletti G, Stogniew M, Allen JE, Giannakakou P, Elemento O.  2019.  A Bayesian machine learning approach for drug target identification using diverse data types.. Nat Commun. 10(1):5221.

Valls E, Lobry C, Geng H, Wang L, Cardenas M, Rivas M, Cerchietti L, Oh P, Yang SNing, Oswald E et al..  2017.  BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells.. Cancer Discov. 7(5):506-521.

Ci W, Polo JM, Cerchietti L, Shaknovich R, Wang L, Yang SNing, Ye K, Farinha P, Horsman DE, Gascoyne RD et al..  2009.  The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL.. Blood. 113(22):5536-48.

Madhukar NS, Elemento O.  2018.  Bioinformatics Approaches to Predict Drug Responses from Genomic Sequencing.. Methods Mol Biol. 1711:277-296.

Sailer V, Schiffman MH, Kossai M, Cyrta J, Beg S, Sullivan B, Pua BB, Lee KSteve, Talenfeld AD, Nanus DM et al..  2018.  Bone biopsy protocol for advanced prostate cancer in the era of precision medicine.. Cancer. 124(5):1008-1015.