Publications

Gilani A, Stein BD, Hoffmann A, de Lima RPereira, Ha EE, Homan EA, Ma L, Rubio-Navarro A, Wun TTha Ra, Carrascal GJose Ayala et al..  2026.  Secretory kinase FAM20C triggers adipocyte dysfunction, inciting insulin resistance and inflammation in obesity.. J Clin Invest. 136(1)

Kim J, Ravichandran H, Yoffe L, Bhinder B, Finos K, Singh A, Pua BB, Bates S, Huang BEmma, Rendeiro AF et al..  2025.  Simultaneous immunomodulation and epithelial-to-mesenchymal transition drives lung adenocarcinoma progression.. bioRxiv.

Park J, De Gregorio R, Hissong E, Ozcelik E, Bartelo N, Dezem FSegato, Zhang L, Marção M, Chasteen H, Zheng Y et al..  2025.  The Spatial Atlas of Human Anatomy (SAHA): A Multimodal Subcellular-Resolution Reference Across Human Organs.. bioRxiv.

Rubinelli L, Manzo OLaura, Sungho J, Del Gaudio I, Bareja R, Marino A, Palikhe S, Di Mauro V, Bucci M, Falcone DJ et al..  2025.  Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases.. Nat Commun. 16(1):1968.

Ovejero S, Devin J, Alibert L, Soun C, Lin Y-L, Dutrieux L, Abouladze M, de Paco EGarcia, Gadacha OKarmous, Constantinou A et al..  2025.  Synthetic Lethal Combinations of DNA Repair Inhibitors and Genotoxic Agents to Target High-Risk Diffuse Large B Cell Lymphoma.. Hematol Oncol. 43(5):e70131.

Altorki NK, Bhinder B, Borczuk AC, Elemento O, Mittal V, McGraw TE.  2024.  A signature of enhanced proliferation associated with response and survival to anti-PD-L1 therapy in early-stage non-small cell lung cancer.. Cell Rep Med. 5(3):101438.

Rajendran S, Hu Y, Canella A, Peterson C, Gross A, Cam M, Nazzaro M, Haffey A, Serin-Harmanci A, Distefano R et al..  2023.  Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma.. Cell Rep. 42(3):112197.

You J, Reilly MD, Eljalby M, Bareja R, Yusupova M, Vyas NS, Bang J, Ding W, Desman G, Miller LS et al..  2023.  Soluble adenylyl cyclase contributes to imiquimod-mediated inflammation and is a potential therapeutic target in psoriasis.. Exp Dermatol. 32(7):1051-1062.

Luo Y, Yamada M, N'Tumba-Byn T, Asif H, Gao M, Hu Y, Marangoni P, Liu Y, Evans T, Rafii S et al..  2023.  SPRY4-dependent ERK negative feedback demarcates functional adult stem cells in the male mouse germline†.. Biol Reprod. 109(4):533-551.

Laurent P, Yang C, Rendeiro AF, Nilsson-Payant BE, Carrau L, Chandar V, Bram Y, tenOever BR, Elemento O, Ivashkiv LB et al..  2022.  Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19.. Sci Immunol. 7(75):eadd4906.

Shohdy KS, Villamar DM, Cao Y, Trieu J, Price KS, Nagy R, Tagawa ST, Molina AM, Sternberg CN, Nanus DM et al..  2022.  Serial ctDNA analysis predicts clinical progression in patients with advanced urothelial carcinoma.. Br J Cancer. 126(3):430-439.

Kulm S, Kofman L, Mezey J, Elemento O.  2022.  Simple Linear Cancer Risk Prediction Models With Novel Features Outperform Complex Approaches.. JCO Clin Cancer Inform. 6:e2100166.

Park J, Kim J, Lewy T, Rice CM, Elemento O, Rendeiro AF, Mason CE.  2022.  Spatial omics technologies at multimodal and single cell/subcellular level.. Genome Biol. 23(1):256.

Park J, Foox J, Hether T, Danko DC, Warren S, Kim Y, Reeves J, Butler DJ, Mozsary C, Rosiene J et al..  2022.  System-wide transcriptome damage and tissue identity loss in COVID-19 patients.. Cell Rep Med. 3(2):100522.

Rivas MA, Meydan C, Chin CR, Challman MF, Kim D, Bhinder B, Kloetgen A, Viny AD, Teater MR, McNally DR et al..  2021.  Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.. Nat Immunol. 22(2):240-253.

Manohar J, Abedian S, Martini R, Kulm S, Salvatore M, Ho K, Christos P, Campion T, Imperato-McGinley J, Ibrahim S et al..  2021.  Social and Clinical Determinants of COVID-19 Outcomes: Modeling Real-World Data from a Pandemic Epicenter.. medRxiv.

Rendeiro AF, Ravichandran H, Bram Y, Chandar V, Kim J, Meydan C, Park J, Foox J, Hether T, Warren S et al..  2021.  The spatial landscape of lung pathology during COVID-19 progression.. Nature. 593(7860):564-569.

Park J, Foox J, Hether T, Danko D, Warren S, Kim Y, Reeves J, Butler DJ, Mozsary C, Rosiene J et al..  2021.  Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps.. bioRxiv.

Ricker E, Verma A, Marullo R, Gupta S, Ye C, Pannellini T, Manni M, Tam W, Inghirami G, Elemento O et al..  2020.  Selective dysregulation of ROCK2 activity promotes aberrant transcriptional networks in ABC diffuse large B-cell lymphoma.. Sci Rep. 10(1):13094.

De Micheli AJ, Laurilliard EJ, Heinke CL, Ravichandran H, Fraczek P, Soueid-Baumgarten S, De Vlaminck I, Elemento O, Cosgrove BD.  2020.  Single-Cell Analysis of the Muscle Stem Cell Hierarchy Identifies Heterotypic Communication Signals Involved in Skeletal Muscle Regeneration.. Cell Rep. 30(10):3583-3595.e5.

Lehmann GL, Hanke-Gogokhia C, Hu Y, Bareja R, Salfati Z, Ginsberg M, Nolan DJ, Mendez-Huergo SP, Dalotto-Moreno T, Wojcinski A et al..  2020.  Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid.. J Exp Med. 217(6)

Conteduca V, Ku S-Y, Puca L, Slade M, Fernandez L, Hess J, Bareja R, Vlachostergios PJ, Sigouros M, Mosquera JMiguel et al..  2020.  SLFN11 Expression in Advanced Prostate Cancer and Response to Platinum-based Chemotherapy.. Mol Cancer Ther. 19(5):1157-1164.

Auguste A, Blanc-Durand F, Deloger M, Le Formal A, Bareja R, Wilkes DC, Richon C, Brunn B, Caron O, Devouassoux-Shisheboran M et al..  2020.  Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) beyond Mutations: A Comprehensive Genomic Analysis.. Cells. 9(6)

Rendeiro AFigueiredo, Ravichandran H, Bram Y, Salvatore S, Borczuk A, Elemento O, Schwartz REdward.  2020.  The spatio-temporal landscape of lung pathology in SARS-CoV-2 infection.. medRxiv.

Iaea DB, Spahr ZR, Singh RK, Chan RB, Zhou B, Bareja R, Elemento O, Di Paolo G, Zhang X, Maxfield FR.  2020.  Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis.. Biochim Biophys Acta Mol Cell Biol Lipids. 1865(4):158609.