Publications

Rivas MA, Meydan C, Chin CR, Challman MF, Kim D, Bhinder B, Kloetgen A, Viny AD, Teater MR, McNally DR et al..  2021.  Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.. Nat Immunol. 22(2):240-253.

Manohar J, Abedian S, Martini R, Kulm S, Salvatore M, Ho K, Christos P, Campion T, Imperato-McGinley J, Ibrahim S et al..  2021.  Social and Clinical Determinants of COVID-19 Outcomes: Modeling Real-World Data from a Pandemic Epicenter.. medRxiv.

Rendeiro AF, Ravichandran H, Bram Y, Chandar V, Kim J, Meydan C, Park J, Foox J, Hether T, Warren S et al..  2021.  The spatial landscape of lung pathology during COVID-19 progression.. Nature. 593(7860):564-569.

Park J, Foox J, Hether T, Danko D, Warren S, Kim Y, Reeves J, Butler DJ, Mozsary C, Rosiene J et al..  2021.  Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps.. bioRxiv.

Ricker E, Verma A, Marullo R, Gupta S, Ye C, Pannellini T, Manni M, Tam W, Inghirami G, Elemento O et al..  2020.  Selective dysregulation of ROCK2 activity promotes aberrant transcriptional networks in ABC diffuse large B-cell lymphoma.. Sci Rep. 10(1):13094.

De Micheli AJ, Laurilliard EJ, Heinke CL, Ravichandran H, Fraczek P, Soueid-Baumgarten S, De Vlaminck I, Elemento O, Cosgrove BD.  2020.  Single-Cell Analysis of the Muscle Stem Cell Hierarchy Identifies Heterotypic Communication Signals Involved in Skeletal Muscle Regeneration.. Cell Rep. 30(10):3583-3595.e5.

Lehmann GL, Hanke-Gogokhia C, Hu Y, Bareja R, Salfati Z, Ginsberg M, Nolan DJ, Mendez-Huergo SP, Dalotto-Moreno T, Wojcinski A et al..  2020.  Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid.. J Exp Med. 217(6)

Conteduca V, Ku S-Y, Puca L, Slade M, Fernandez L, Hess J, Bareja R, Vlachostergios PJ, Sigouros M, Mosquera JMiguel et al..  2020.  SLFN11 Expression in Advanced Prostate Cancer and Response to Platinum-based Chemotherapy.. Mol Cancer Ther. 19(5):1157-1164.

Auguste A, Blanc-Durand F, Deloger M, Le Formal A, Bareja R, Wilkes DC, Richon C, Brunn B, Caron O, Devouassoux-Shisheboran M et al..  2020.  Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) beyond Mutations: A Comprehensive Genomic Analysis.. Cells. 9(6)

Rendeiro AFigueiredo, Ravichandran H, Bram Y, Salvatore S, Borczuk A, Elemento O, Schwartz REdward.  2020.  The spatio-temporal landscape of lung pathology in SARS-CoV-2 infection.. medRxiv.

Iaea DB, Spahr ZR, Singh RK, Chan RB, Zhou B, Bareja R, Elemento O, Di Paolo G, Zhang X, Maxfield FR.  2020.  Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis.. Biochim Biophys Acta Mol Cell Biol Lipids. 1865(4):158609.

Bhardwaj P, Ikeda T, Zhou XKathy, Wang H, Zheng XEmily, Giri DD, Elemento O, Verma A, Miyazawa M, Mukherjee S et al..  2019.  Supplemental estrogen and caloric restriction reduce obesity-induced periprostatic white adipose inflammation in mice.. Carcinogenesis. 40(7):914-923.

Aronova A, Min IM, Crowley MJP, Panjwani SJ, Finnerty BM, Scognamiglio T, Liu Y-F, Whitsett TG, Garg S, Demeure MJ et al..  2018.  STMN1 is Overexpressed in Adrenocortical Carcinoma and Promotes a More Aggressive Phenotype In Vitro.. Ann Surg Oncol. 25(3):792-800.

Poran A, Nötzel C, Aly O, Mencia-Trinchant N, Harris CT, Guzman ML, Hassane DC, Elemento O, Kafsack BFC.  2017.  Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites.. Nature. 551(7678):95-99.

Schachterle W, Badwe CR, Palikuqi B, Kunar B, Ginsberg M, Lis R, Yokoyama M, Elemento O, Scandura JM, Rafii S.  2017.  Sox17 drives functional engraftment of endothelium converted from non-vascular cells.. Nat Commun. 8:13963.

Ge Y, Gomez NC, Adam RC, Nikolova M, Yang H, Verma A, Lu CPei-Ju, Polak L, Yuan S, Elemento O et al..  2017.  Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.. Cell. 169(4):636-650.e14.

Giannopoulou E, Elemento O.  2017.  Systematic Discovery of Chromatin-Bound Protein Complexes from ChIP-seq Datasets.. Methods Mol Biol. 1507:43-58.

Nwachukwu JC, Srinivasan S, Bruno NE, Nowak J, Wright NJ, Minutolo F, Rangarajan ES, Izard T, Yao X-Q, Grant BJ et al..  2017.  Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.. Cell Chem Biol. 24(1):35-45.

Redmond D, Poran A, Elemento O.  2016.  Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq.. Genome Med. 8(1):80.

Alinari L, Mahasenan KV, Yan F, Karkhanis V, Chung J-H, Smith EM, Quinion C, Smith PL, Kim L, Patton JT et al..  2015.  Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation.. Blood. 125(16):2530-43.

Kleiman DA, Beninato T, Sultan S, Crowley MJP, Finnerty B, Kumar R, Panarelli NC, Liu Y-F, Lieberman MD, Seandel M et al..  2014.  Silencing of UCHL1 by CpG promoter hyper-methylation is associated with metastatic gastroenteropancreatic well-differentiated neuroendocrine (carcinoid) tumors.. Ann Surg Oncol. 21 Suppl 4:S672-9.

Sun X-J, Wang Z, Wang L, Jiang Y, Kost N, T Soong D, Chen W-Y, Tang Z, Nakadai T, Elemento O et al..  2013.  A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.. Nature. 500(7460):93-7.

Qiao Y, Giannopoulou EG, Chan CHin, Park S-H, Gong S, Chen J, Hu X, Elemento O, Ivashkiv LB.  2013.  Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling.. Immunity. 39(3):454-69.