Publications

Beltran H, Prandi D, Mosquera JMiguel, Benelli M, Puca L, Cyrta J, Marotz C, Giannopoulou E, Chakravarthi BVSK, Varambally S et al..  2016.  Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer.. Nat Med. 22(3):298-305.

Pritchard CC, Mateo J, Walsh MF, De Sarkar N, Abida W, Beltran H, Garofalo A, Gulati R, Carreira S, Eeles R et al..  2016.  Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.. N Engl J Med. 375(5):443-53.

Pritchard CC, Mateo J, Walsh MF, De Sarkar N, Abida W, Beltran H, Garofalo A, Gulati R, Carreira S, Eeles R et al..  2016.  Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.. N Engl J Med. 375(5):443-53.

Dardenne E, Beltran H, Benelli M, Gayvert K, Berger A, Puca L, Cyrta J, Sboner A, Noorzad Z, MacDonald T et al..  2016.  N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.. Cancer Cell. 30(4):563-577.

Dardenne E, Beltran H, Benelli M, Gayvert K, Berger A, Puca L, Cyrta J, Sboner A, Noorzad Z, MacDonald T et al..  2016.  N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.. Cancer Cell. 30(4):563-577.

Nwachukwu JC, Srinivasan S, Zheng Y, Wang S, Min J, Dong C, Liao Z, Nowak J, Wright NJ, Houtman R et al..  2016.  Predictive features of ligand-specific signaling through the estrogen receptor.. Mol Syst Biol. 12(4):864.

Cárdenas MG, Yu W, Béguelin W, Teater MR, Geng H, Goldstein RL, Oswald E, Hatzi K, Yang S-N, Cohen J et al..  2016.  Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.. J Clin Invest. 126(9):3351-62.

Lis R, Karrasch CC, Poulos MG, Kunar B, Redmond D, Duran JGBarcia, Badwe CR, Schachterle W, Ginsberg M, Xiang J et al..  2017.  Conversion of adult endothelium to immunocompetent haematopoietic stem cells.. Nature. 545(7655):439-445.

Jiang Y, Ortega-Molina A, Geng H, Ying H-Y, Hatzi K, Parsa S, McNally D, Wang L, Doane AS, Agirre X et al..  2017.  CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.. Cancer Discov. 7(1):38-53.

Du W, Goldstein R, Jiang Y, Aly O, Cerchietti L, Melnick A, Elemento O.  2017.  Effective Combination Therapies for B-cell Lymphoma Predicted by a Virtual Disease Model.. Cancer Res. 77(8):1818-1830.

Glass JL, Hassane D, Wouters BJ, Kunimoto H, Avellino R, Garrett-Bakelman FE, Guryanova OA, Bowman R, Redlich S, Intlekofer AM et al..  2017.  Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.. Cancer Discov. 7(8):868-883.

Romanel A, Zhang T, Elemento O, Demichelis F.  2017.  EthSEQ: ethnicity annotation from whole exome sequencing data.. Bioinformatics. 33(15):2402-2404.

Romanel A, Garritano S, Stringa B, Blattner M, Dalfovo D, Chakravarty D, Soong D, Cotter KA, Petris G, Dhingra P et al..  2017.  Inherited determinants of early recurrent somatic mutations in prostate cancer.. Nat Commun. 8(1):48.

Romanel A, Garritano S, Stringa B, Blattner M, Dalfovo D, Chakravarty D, Soong D, Cotter KA, Petris G, Dhingra P et al..  2017.  Inherited determinants of early recurrent somatic mutations in prostate cancer.. Nat Commun. 8(1):48.

Romanel A, Garritano S, Stringa B, Blattner M, Dalfovo D, Chakravarty D, Soong D, Cotter KA, Petris G, Dhingra P et al..  2017.  Inherited determinants of early recurrent somatic mutations in prostate cancer.. Nat Commun. 8(1):48.

Mendoza A, Fang V, Chen C, Serasinghe M, Verma A, Muller J, V Chaluvadi S, Dustin ML, Hla T, Elemento O et al..  2017.  Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells.. Nature. 546(7656):158-161.

Amengual JE, Prabhu SA, Lombardo M, Zullo K, Johannet PM, Gonzalez Y, Scotto L, Serrano XJirau, Wei Y, Duong J et al..  2017.  Mechanisms of Acquired Drug Resistance to the HDAC6 Selective Inhibitor Ricolinostat Reveals Rational Drug-Drug Combination with Ibrutinib.. Clin Cancer Res. 23(12):3084-3096.

Pisapia DJ, Salvatore S, Pauli C, Hissong E, Eng K, Prandi D, Sailer V-W, Robinson BD, Park K, Cyrta J et al..  2017.  Next-Generation Rapid Autopsies Enable Tumor Evolution Tracking and Generation of Preclinical Models.. JCO Precis Oncol. 2017

Pauli C, Hopkins BD, Prandi D, Shaw R, Fedrizzi T, Sboner A, Sailer V, Augello M, Puca L, Rosati R et al..  2017.  Personalized and Cancer Models to Guide Precision Medicine.. Cancer Discov. 7(5):462-477.

Liberti MV, Dai Z, Wardell SE, Baccile JA, Liu X, Gao X, Baldi R, Mehrmohamadi M, Johnson MO, Madhukar NS et al..  2017.  A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product.. Cell Metab. 26(4):648-659.e8.

Doane AS, Elemento O.  2017.  Regulatory elements in molecular networks.. Wiley Interdiscip Rev Syst Biol Med. 9(3)

Mauer J, Luo X, Blanjoie A, Jiao X, Grozhik AV, Patil DP, Linder B, Pickering BF, Vasseur J-J, Chen Q et al..  2017.  Reversible methylation of mA in the 5' cap controls mRNA stability.. Nature. 541(7637):371-375.

Dave B, Gonzalez DD, Bin Liu Z-, Li X, Wong H, Granados S, Ezzedine NE, Sieglaff DH, Ensor JE, Miller KD et al..  2017.  Role of RPL39 in Metaplastic Breast Cancer.. J Natl Cancer Inst. 109(6)

Han T, Schatoff EM, Murphy C, Zafra MPaz, Wilkinson JE, Elemento O, Dow LE.  2017.  R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine.. Nat Commun. 8:15945.

Liu Y, Pelham-Webb B, Di Giammartino DCampigli, Li J, Kim D, Kita K, Saiz N, Garg V, Doane A, Giannakakou P et al..  2017.  Widespread Mitotic Bookmarking by Histone Marks and Transcription Factors in Pluripotent Stem Cells.. Cell Rep. 19(7):1283-1293.