Publications

Elemento O.  2016.  KLF4: A new player in plasma cell development.. Cell Cycle. 15(20):2691-2.

Elemento O, Tavazoie S.  2007.  Fastcompare: a nonalignment approach for genome-scale discovery of DNA and mRNA regulatory elements using network-level conservation.. Methods Mol Biol. 395:349-66.

Elemento O, Gascuel O, Lefranc M-P.  2002.  Reconstructing the duplication history of tandemly repeated genes.. Mol Biol Evol. 19(3):278-88.

Elemento O, Khozin S, Sternberg CN.  2025.  The use of artificial intelligence for cancer therapeutic decision-making.. NEJM AI. 2(5)

Elemento O.  2021.  Towards artificial intelligence-driven pathology assessment for hematological malignancies.. Blood Cancer Discov. 2(3):195-197.

Elemento O.  2021.  The road from Rous sarcoma virus to precision medicine.. J Exp Med. 218(4)

Elkhader J, Elemento O.  2022.  Artificial intelligence in oncology: From bench to clinic.. Semin Cancer Biol. 84:113-128.

Erler P, Keutgen XM, Crowley MJ, Zetoune T, Kundel A, Kleiman D, Beninato T, Scognamiglio T, Elemento O, Zarnegar R et al..  2014.  Dicer expression and microRNA dysregulation associate with aggressive features in thyroid cancer.. Surgery. 156(6):1342-50;discussion1350.

Ertl IE, Lemberger U, Ilijazi D, Hassler MR, Bruchbacher A, Brettner R, Kronabitter H, Gutmann M, Vician P, Zeitler G et al..  2022.  Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound.. Eur Urol. 82(3):261-270.

Faltas BM, Prandi D, Tagawa ST, Molina AM, Nanus DM, Sternberg C, Rosenberg J, Mosquera JMiguel, Robinson B, Elemento O et al..  2016.  Clonal evolution of chemotherapy-resistant urothelial carcinoma.. Nat Genet. 48(12):1490-1499.

Falvo DJ, Grimont A, Zumbo P, Fall WB, Yang JL, Osterhoudt A, Pan G, Rendeiro AF, Meng Y, Wilkinson JE et al..  2023.  A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas.. Dev Cell. 58(24):2959-2973.e7.

Faria M, Karami S, Granados-Principal S, Dey P, Verma A, Choi DS, Elemento O, Bawa-Khalfe T, Chang JC, Strom AM et al..  2018.  The ERβ4 variant induces transformation of the normal breast mammary epithelial cell line MCF-10A; the ERβ variants ERβ2 and ERβ5 increase aggressiveness of TNBC by regulation of hypoxic signaling.. Oncotarget. 9(15):12201-12211.

Fernandez EM, Eng K, Beg S, Beltran H, Faltas BM, Mosquera JMiguel, Nanus DM, Pisapia DJ, Rao RA, Robinson BD et al..  2019.  Cancer-Specific Thresholds Adjust for Whole Exome Sequencing-based Tumor Mutational Burden Distribution.. JCO Precis Oncol. 3

Finnerty BM, Moore MD, Verma A, Aronova A, Huang S, Edwards DP, Chen Z, Seandel M, Scognamiglio T, Du Y-CNancy et al..  2019.  UCHL1 loss alters the cell-cycle in metastatic pancreatic neuroendocrine tumors.. Endocr Relat Cancer. 26(4):411-423.

Fiore D, Cappelli LVincenzo, Zhaoqi L, Kotlov N, Sorokina M, Phillip J, Zumbo P, Yoffe L, Ghione P, Wang A et al..  2025.  A patient-derived T cell lymphoma biorepository uncovers pathogenetic mechanisms and host-related therapeutic vulnerabilities.. Cell Rep Med. 6(4):102029.

Fontugne J, Cai PY, Alnajar H, Bhinder B, Park K, Ye H, Beg S, Sailer V, Siddiqui J, Blattner-Johnson M et al..  2022.  Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci.. JCI Insight. 7(4)

Franceschini GMarco, Quaini O, Mizuno K, Orlando F, Ciani Y, Ku S-Y, Sigouros M, Rothmann E, Alonso A, Benelli M et al..  2024.  Noninvasive Detection of Neuroendocrine Prostate Cancer through Targeted Cell-free DNA Methylation.. Cancer Discov. 14(3):424-445.

Furlow PW, Zhang S, T Soong D, Halberg N, Goodarzi H, Mangrum C, Y Wu G, Elemento O, Tavazoie SF.  2015.  Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival.. Nat Cell Biol. 17(7):943-52.

Galletti G, Halima A, Gjyrezi A, Zhang J, Zimmerman B, Worroll D, Kallergi G, Barreja R, Ocean A, Saxena A et al..  2024.  Transferrin receptor-based circulating tumor cell enrichment provides a snapshot of the molecular landscape of solid tumors and correlates with clinical outcomes.. medRxiv.

Gambi G, Di Simone E, Basso V, Ricci L, Wang R, Verma A, Elemento O, Ponzoni M, Inghirami G, Icardi L et al..  2019.  The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3.. Cancer Res. 79(12):3076-3087.

Gayvert KM, Madhukar NS, Elemento O.  2016.  A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials.. Cell Chem Biol. 23(10):1294-1301.

Gayvert K, Elemento O.  2019.  Drug-Induced Expression-Based Computational Repurposing of Small Molecules Affecting Transcription Factor Activity.. Methods Mol Biol. 1903:179-184.

Gayvert KM, Aly O, Platt J, Bosenberg MW, Stern DF, Elemento O.  2017.  A Computational Approach for Identifying Synergistic Drug Combinations.. PLoS Comput Biol. 13(1):e1005308.

Gayvert KM, Dardenne E, Cheung C, Boland MRegina, Lorberbaum T, Wanjala J, Chen Y, Rubin MA, Tatonetti NP, Rickman DS et al..  2016.  A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors.. Cell Rep. 15(11):2348-56.

Ge Y, Gomez NC, Adam RC, Nikolova M, Yang H, Verma A, Lu CPei-Ju, Polak L, Yuan S, Elemento O et al..  2017.  Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.. Cell. 169(4):636-650.e14.