Elemento Lab

Publications

Found 506 results
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Ricker E, Verma A, Marullo R, Gupta S, Ye C, Pannellini T, Manni M, Tam W, Inghirami G, Elemento O et al..  2020.  Selective dysregulation of ROCK2 activity promotes aberrant transcriptional networks in ABC diffuse large B-cell lymphoma.. Sci Rep. 10(1):13094.
Gilani A, Stein BD, Hoffmann A, de Lima RPereira, Ha EE, Homan EA, Ma L, Rubio-Navarro A, Wun TTha Ra, Carrascal GJose Ayala et al..  2026.  Secretory kinase FAM20C triggers adipocyte dysfunction, inciting insulin resistance and inflammation in obesity.. J Clin Invest. 136(1)
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Han T, Schatoff EM, Murphy C, Zafra MPaz, Wilkinson JE, Elemento O, Dow LE.  2017.  R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine.. Nat Commun. 8:15945.
Dave B, Gonzalez DD, Bin Liu Z-, Li X, Wong H, Granados S, Ezzedine NE, Sieglaff DH, Ensor JE, Miller KD et al..  2017.  Role of RPL39 in Metaplastic Breast Cancer.. J Natl Cancer Inst. 109(6)
Morash M, Mitchell H, Beltran H, Elemento O, Pathak J.  2018.  The Role of Next-Generation Sequencing in Precision Medicine: A Review of Outcomes in Oncology.. J Pers Med. 8(3)
Vicario R, Fragkogianni S, Pokrovskii M, Meyer C, Lopez-Rodrigo E, Hu Y, Ogishi M, Alberdi A, Baako A, Ay O et al..  2025.  Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration.. Neuron. 113(7):1065-1081.e13.
Elemento O.  2021.  The road from Rous sarcoma virus to precision medicine.. J Exp Med. 218(4)
Kassambara A, Herviou L, Ovejero S, Jourdan M, Thibaut C, Vikova V, Pasero P, Elemento O, Moreaux J.  2021.  RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators.. Leukemia. 35(5):1451-1462.
Manzo OL, Nour J, Sasset L, Marino A, Rubinelli L, Palikhe S, Smimmo M, Hu Y, Bucci MRosaria, Borczuk A et al..  2024.  Rewiring Endothelial Sphingolipid Metabolism to Favor S1P Over Ceramide Protects From Coronary Atherosclerosis.. Circ Res. 134(8):990-1005.
Bancells C, Llorà-Batlle O, Poran A, Nötzel C, Rovira-Graells N, Elemento O, Kafsack BFC, Cortés A.  2019.  Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum.. Nat Microbiol. 4(1):144-154.
Mauer J, Luo X, Blanjoie A, Jiao X, Grozhik AV, Patil DP, Linder B, Pickering BF, Vasseur J-J, Chen Q et al..  2017.  Reversible methylation of mA in the 5' cap controls mRNA stability.. Nature. 541(7637):371-375.
Falvo DJ, Grimont A, Zumbo P, Fall WB, Yang JL, Osterhoudt A, Pan G, Rendeiro AF, Meng Y, Wilkinson JE et al..  2023.  A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas.. Dev Cell. 58(24):2959-2973.e7.
Chan CS, Elemento O, Tavazoie S.  2005.  Revealing posttranscriptional regulatory elements through network-level conservation.. PLoS Comput Biol. 1(7):e69.
Goodarzi H, Elemento O, Tavazoie S.  2009.  Revealing global regulatory perturbations across human cancers.. Mol Cell. 36(5):900-11.
Ullmann TM, Thiesmeyer JW, Lee YJoo, Beg S, Mosquera JMiguel, Elemento O, Fahey TJ, Scognamiglio T, Houvras Y.  2022.  RET Fusion-Positive Papillary Thyroid Cancers are Associated with a More Aggressive Phenotype.. Ann Surg Oncol.
Sandler VM, Lis R, Liu Y, Kedem A, James D, Elemento O, Butler JM, Scandura JM, Rafii S.  2014.  Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.. Nature. 511(7509):312-8.
Ha ET, Taylor KD, Raffield LM, Briggs M, Yee A, Elemento O, Parikh M, Peterson SJ, Frishman W, Gerszten RE et al..  2023.  The Relationship of Duffy Gene Polymorphism, High Sensitivity C-Reactive Protein, and Long-term Outcomes.. medRxiv.
Doane AS, Elemento O.  2017.  Regulatory elements in molecular networks.. Wiley Interdiscip Rev Syst Biol Med. 9(3)
De Micheli AJ, Spector JA, Elemento O, Cosgrove BD.  2020.  A reference single-cell transcriptomic atlas of human skeletal muscle tissue reveals bifurcated muscle stem cell populations.. Skelet Muscle. 10(1):19.
Akinsanya K, AlQuraishi M, Boija A, Chodera J, Cichońska A, Ghassemi M, Head M, Jin W, Kibbe WA, Krogan N et al..  2025.  Redefining druggable targets with artificial intelligence.. Nat Biotechnol. 43(9):1416-1418.
Elemento O, Gascuel O, Lefranc M-P.  2002.  Reconstructing the duplication history of tandemly repeated genes.. Mol Biol Evol. 19(3):278-88.
Cárdenas MG, Yu W, Béguelin W, Teater MR, Geng H, Goldstein RL, Oswald E, Hatzi K, Yang S-N, Cohen J et al..  2016.  Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.. J Clin Invest. 126(9):3351-62.
Chiaretti S, Messina M, Grammatico S, Piciocchi A, Fedullo AL, Di Giacomo F, Peragine N, Gianfelici V, Lauretti A, Bareja R et al..  2018.  Rapid identification of BCR/ABL1-like acute lymphoblastic leukaemia patients using a predictive statistical model based on quantitative real time-polymerase chain reaction: clinical, prognostic and therapeutic implications.. Br J Haematol. 181(5):642-652.
Gucalp A, Zhou XK, Cook ED, Garber JE, Crew KD, Nangia JR, Bhardwaj P, Giri DD, Elemento O, Verma A et al..  2018.  A Randomized Multicenter Phase II Study of Docosahexaenoic Acid in Patients with a History of Breast Cancer, Premalignant Lesions, or Benign Breast Disease.. Cancer Prev Res (Phila). 11(4):203-214.
Lhuillier C, Rudqvist N-P, Elemento O, Formenti SC, Demaria S.  2019.  Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system.. Genome Med. 11(1):40.