Elemento Lab

Publications

Found 504 results
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Xie XP, Laks DR, Sun D, Poran A, Laughney AM, Wang Z, Sam J, Belenguer G, Fariñas I, Elemento O et al..  2020.  High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging.. Proc Natl Acad Sci U S A. 117(49):31448-31458.
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Sun M, Zhao S, Gilvary C, Elemento O, Zhou J, Wang F.  2020.  Graph convolutional networks for computational drug development and discovery.. Brief Bioinform. 21(3):919-935.
Kassambara A, Jourdan M, Bruyer A, Robert N, Pantesco V, Elemento O, Klein B, Moreaux J.  2017.  Global miRNA expression analysis identifies novel key regulators of plasma cell differentiation and malignant plasma cell.. Nucleic Acids Res. 45(10):5639-5652.
Altorki NK, Borczuk AC, Harrison S, Groner LK, Bhinder B, Mittal V, Elemento O, McGraw TE.  2022.  Global evolution of the tumor microenvironment associated with progression from preinvasive invasive to invasive human lung adenocarcinoma.. Cell Rep. 39(1):110639.
Jessurun J, Orr C, McNulty SN, Hagen CE, Alnajar H, Wilkes D, Kudman S, Assaad MAl, Dorsaint P, Ohara K et al..  2023.  GLI1 -Rearranged Enteric Tumor : Expanding the Spectrum of Gastrointestinal Neoplasms With GLI1 Gene Fusions.. Am J Surg Pathol. 47(1):65-73.
van der Mijn JC, Eng KW, Chandra P, Fernandez E, Ramazanoglu S, Sigaras A, Oromendia C, Gudas LJ, Tagawa ST, Nanus DM et al..  2022.  The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.. Mol Oncol. 16(12):2384-2395.
Wolujewicz P, Aguiar-Pulido V, AbdelAleem A, Nair V, Thareja G, Suhre K, Shaw GM, Finnell RH, Elemento O, M Ross E.  2021.  Genome-wide investigation identifies a rare copy-number variant burden associated with human spina bifida.. Genet Med. 23(7):1211-1218.
Jiang Y, T Soong D, Wang L, Melnick AM, Elemento O.  2012.  Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma.. PLoS One. 7(7):e40332.
Kulm S, Langhans MT, Shen TS, Kolin DA, Elemento O, Rodeo SA.  2022.  Genome-Wide Association Study of Adhesive Capsulitis Suggests Significant Genetic Risk Factors.. J Bone Joint Surg Am. 104(21):1869-1876.
Umesh A, Cordogan S, Simpson SK, Bram JT, Jones RH, Schairer WW, Sboner A, Elemento O, Green DW, Fabricant PD.  2026.  Genetic Variants Related to TGF-β Signaling Pathway Modulate Risk of Meniscus Injury: A Multiancestry Genome-wide Association Study.. Clin Orthop Relat Res. 484(1):178-193.
Kulm S, Kaidi AC, Kolin D, Langhans MT, Bostrom MP, Elemento O, Shen TS.  2023.  Genetic Risk Factors for End-Stage Hip Osteoarthritis Treated With Total Hip Arthroplasty: A Genome-wide Association Study.. J Arthroplasty. 38(10):2149-2153.e1.
Rath P, Huang C, Wang T, Wang T, Li H, Prados-Rosales R, Elemento O, Casadevall A, Nathan CF.  2013.  Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 110(49):E4790-7.
Chen HJoyce, Poran A, Unni AM, Huang SXuelian, Elemento O, Snoeck H-W, Varmus H.  2019.  Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells.. J Exp Med. 216(3):674-687.
Tang CP, Clark O, Ferrarone JR, Campos C, Lalani AS, Chodera JD, Intlekofer AM, Elemento O, Mellinghoff IK.  2022.  GCN2 kinase activation by ATP-competitive kinase inhibitors.. Nat Chem Biol. 18(2):207-215.
Xu X, Wang K, Vera O, Verma A, Jasani N, Bok I, Elemento O, Du D, Yu X, Karreth FA.  2022.  Gain of Chromosome 1q Perturbs a Competitive Endogenous RNA Network to Promote Melanoma Metastasis.. Cancer Res. 82(17):3016-3031.
Ladewig MS, Jacobsen JOB, Wagner AH, Danis D, Kassaby BEl, Gargano M, Groza T, Baudis M, Steinhaus R, Seelow D et al..  2023.  GA4GH Phenopackets: A Practical Introduction.. Adv Genet (Hoboken). 4(1):2200016.
Jacobsen JOB, Baudis M, Baynam GS, Beckmann JS, Beltran S, Buske OJ, Callahan TJ, Chute CG, Courtot M, Danis D et al..  2022.  The GA4GH Phenopacket schema defines a computable representation of clinical data.. Nat Biotechnol. 40(6):817-820.
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Elemento O.  2020.  The future of precision medicine: towards a more predictive personalized medicine.. Emerg Top Life Sci. 4(2):175-177.
Pisapia DJ, Ohara K, Bareja R, Wilkes DC, Hissong E, Croyle JA, Kim J-H, Saab J, MacDonald TY, Beg S et al..  2020.  Fusions involving BCOR and CREBBP are rare events in infiltrating glioma.. Acta Neuropathol Commun. 8(1):80.
Claridge SE, Nath S, Baum A, Farias R, Cavallo J-A, Rizvi NM, De Boni L, Park E, Granados GLara, Hauesgen M et al..  2025.  Functional genomics pipeline identifies CRL4 inhibition for the treatment of ovarian cancer.. Clin Transl Med. 15(2):e70078.
Choi S, Wang D, Chen X, Tang LH, Verma A, Chen Z, Kim BJung, Selesner L, Robzyk K, Zhang G et al..  2019.  Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression.. Mol Cancer. 18(1):92.
Jang J-Y, Hwang I, Pan H, Yao J, Alinari L, Imada E, Zanettini C, Kluk MJ, Wang Y, Lee Y et al..  2022.  A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas.. J Clin Invest. 132(24)
Rajendran S, Rehani E, Phu W, Zhan Q, Malmsten JE, Meseguer M, Miller KA, Rosenwaks Z, Elemento O, Zaninovic N et al..  2025.  A foundational model for in vitro fertilization trained on 18 million time-lapse images.. Nat Commun. 16(1):6235.
Chen HJoyce, Gardner EE, Shah Y, Zhang K, Thakur A, Zhang C, Elemento O, Varmus H.  2024.  FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS.. bioRxiv.
Reichel JB, McCormick J, Fromm JR, Elemento O, Cesarman E, Roshal M.  2017.  Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma.. J Vis Exp. (124)