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X
Y
Z
O
Chakravarty D
,
Sboner A
,
Nair SS
,
Giannopoulou E
,
Li R
,
Hennig S
,
Mosquera JMiguel
,
Pauwels J
,
Park K
,
Kossai M
et al.
. 2014.
The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer.
.
Nat Commun. 5:5383.
Seo BRi
,
Bhardwaj P
,
Choi S
,
Gonzalez J
,
Eguiluz RCAndresen
,
Wang K
,
Mohanan S
,
Morris PG
,
Du B
,
Zhou XK
et al.
. 2015.
Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis.
.
Sci Transl Med. 7(301):301ra130.
Springer NL
,
Iyengar NM
,
Bareja R
,
Verma A
,
Jochelson MS
,
Giri DD
,
Zhou XK
,
Elemento O
,
Dannenberg AJ
,
Fischbach C
. 2019.
Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages.
.
Am J Pathol. 189(10):2019-2035.
N
Takemoto A
,
Kawashima SA
,
Li J-J
,
Jeffery L
,
Yamatsugu K
,
Elemento O
,
Nurse P
. 2016.
Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis.
.
J Cell Sci. 129(6):1250-9.
Alsaleem MA
,
Ball G
,
Toss MS
,
Raafat S
,
Aleskandarany M
,
Joseph C
,
Ogden A
,
Bhattarai S
,
Rida PCG
,
Khani F
et al.
. 2020.
A novel prognostic two-gene signature for triple negative breast cancer.
.
Mod Pathol.
Lu Y
,
T Soong D
,
Elemento O
. 2013.
A novel approach for characterizing microsatellite instability in cancer cells.
.
PLoS One. 8(5):e63056.
Berger A
,
Brady NJ
,
Bareja R
,
Robinson B
,
Conteduca V
,
Augello MA
,
Puca L
,
Ahmed A
,
Dardenne E
,
Lu X
et al.
. 2019.
N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.
.
J Clin Invest. 129(9):3924-3940.
Dardenne E
,
Beltran H
,
Benelli M
,
Gayvert K
,
Berger A
,
Puca L
,
Cyrta J
,
Sboner A
,
Noorzad Z
,
MacDonald T
et al.
. 2016.
N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
.
Cancer Cell. 30(4):563-577.
Chang C-Y
,
H Pasolli A
,
Giannopoulou EG
,
Guasch G
,
Gronostajski RM
,
Elemento O
,
Fuchs E
. 2013.
NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche.
.
Nature. 495(7439):98-102.
Pisapia DJ
,
Salvatore S
,
Pauli C
,
Hissong E
,
Eng K
,
Prandi D
,
Sailer V-W
,
Robinson BD
,
Park K
,
Cyrta J
et al.
. 2017.
Next-Generation Rapid Autopsies Enable Tumor Evolution Tracking and Generation of Preclinical Models.
.
JCO Precis Oncol. 2017
Altorki NK
,
McGraw TE
,
Borczuk AC
,
Saxena A
,
Port JL
,
Stiles BM
,
Lee BE
,
Sanfilippo NJ
,
Scheff RJ
,
Pua BB
et al.
. 2021.
Neoadjuvant durvalumab with or without stereotactic body radiotherapy in patients with early-stage non-small-cell lung cancer: a single-centre, randomised phase 2 trial.
.
Lancet Oncol. 22(6):824-835.
M
Rajadhyaksha AM
,
Elemento O
,
Puffenberger EG
,
Schierberl KC
,
Xiang JZ
,
Putorti ML
,
Berciano J
,
Poulin C
,
Brais B
,
Michaelides M
et al.
. 2010.
Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa.
.
Am J Hum Genet. 87(5):643-54.
Nie K
,
Redmond D
,
Eng KW
,
Zhang T
,
Cheng S
,
Mathew S
,
Elemento O
,
Tam W
. 2021.
Mutation landscape, clonal evolution pattern, and potential pathogenic pathways in B-lymphoblastic transformation of follicular lymphoma.
.
Leukemia. 35(4):1203-1208.
Béguelin W
,
Teater M
,
Meydan C
,
Hoehn KB
,
Phillip JM
,
Soshnev AA
,
Venturutti L
,
Rivas MA
,
Calvo-Fernández MT
,
Gutierrez J
et al.
. 2020.
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response.
.
Cancer Cell. 37(5):655-673.e11.
Bunting KL
,
T Soong D
,
Singh R
,
Jiang Y
,
Béguelin W
,
Poloway DW
,
Swed BL
,
Hatzi K
,
Reisacher W
,
Teater M
et al.
. 2016.
Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region.
.
Immunity. 45(3):497-512.
Shah MA
,
Enzinger P
,
Ko AH
,
Ocean AJ
,
Philip PAgop
,
Thakkar PV
,
Cleveland K
,
Lu Y
,
Kortmansky J
,
Christos PJ
et al.
. 2020.
Multicenter Phase II Study of Cabazitaxel in Advanced Gastroesophageal Cancer: Association of HER2 Expression and M2-Like Tumor-Associated Macrophages with Patient Outcome.
.
Clin Cancer Res. 26(18):4756-4766.
Nolan DJ
,
Ginsberg M
,
Israely E
,
Palikuqi B
,
Poulos MG
,
James D
,
Ding B-S
,
Schachterle W
,
Liu Y
,
Rosenwaks Z
et al.
. 2013.
Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration.
.
Dev Cell. 26(2):204-19.
Matrai C
,
Motanagh S
,
Mirabelli S
,
Ma L
,
He B
,
Chapman-Davis E
,
Kurtis B
,
Elemento O
,
Mosquera JMiguel
,
Ellenson LH
. 2020.
Molecular Profiles of Mixed Endometrial Carcinoma.
.
Am J Surg Pathol. 44(8):1104-1111.
Tan AY
,
Michaeel A
,
Liu G
,
Elemento O
,
Blumenfeld J
,
Donahue S
,
Parker T
,
Levine D
,
Rennert H
. 2014.
Molecular diagnosis of autosomal dominant polycystic kidney disease using next-generation sequencing.
.
J Mol Diagn. 16(2):216-28.
Gilvary C
,
Madhukar N
,
Elkhader J
,
Elemento O
. 2019.
The Missing Pieces of Artificial Intelligence in Medicine.
.
Trends Pharmacol Sci. 40(8):555-564.
Chaudhri VK
,
Salzler GG
,
Dick SA
,
Buckman MS
,
Sordella R
,
Karoly ED
,
Mohney R
,
Stiles BM
,
Elemento O
,
Altorki NK
et al.
. 2013.
Metabolic alterations in lung cancer-associated fibroblasts correlated with increased glycolytic metabolism of the tumor.
.
Mol Cancer Res. 11(6):579-92.
Kansler ER
,
Verma A
,
Langdon EM
,
Simon-Vermot T
,
Yin A
,
Lee W
,
Attiyeh M
,
Elemento O
,
White RM
. 2017.
Melanoma genome evolution across species.
.
BMC Genomics. 18(1):136.
Furlow PW
,
Zhang S
,
T Soong D
,
Halberg N
,
Goodarzi H
,
Mangrum C
,
Y Wu G
,
Elemento O
,
Tavazoie SF
. 2015.
Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival.
.
Nat Cell Biol. 17(7):943-52.
Amengual JE
,
Prabhu SA
,
Lombardo M
,
Zullo K
,
Johannet PM
,
Gonzalez Y
,
Scotto L
,
Serrano XJirau
,
Wei Y
,
Duong J
et al.
. 2017.
Mechanisms of Acquired Drug Resistance to the HDAC6 Selective Inhibitor Ricolinostat Reveals Rational Drug-Drug Combination with Ibrutinib.
.
Clin Cancer Res. 23(12):3084-3096.
Gilvary C
,
Elkhader J
,
Madhukar N
,
Henchcliffe C
,
Goncalves MD
,
Elemento O
. 2020.
A machine learning and network framework to discover new indications for small molecules.
.
PLoS Comput Biol. 16(8):e1008098.
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