Publications

Khani F, Hooper WF, Wang X, Chu TR, Shah M, Winterkorn L, Sigouros M, Conteduca V, Pisapia D, Wobker S et al..  2023.  Author Correction: Evolution of structural rearrangements in prostate cancer intracranial metastases.. NPJ Precis Oncol. 7(1):113.

Assaad MAl, Shin N, Sigouros M, Manohar J, Antysheva Z, Kotlov N, Kiriy D, Nikitina A, Kleimenov M, Tsareva A et al..  2023.  Deciphering the origin and therapeutic targets of cancer of unknown primary: a case report that illustrates the power of integrative whole-exome and transcriptome sequencing analysis.. Front Oncol. 13:1274163.

Khani F, Hooper WF, Wang X, Chu TR, Shah M, Winterkorn L, Sigouros M, Conteduca V, Pisapia D, Wobker S et al..  2023.  Evolution of structural rearrangements in prostate cancer intracranial metastases.. NPJ Precis Oncol. 7(1):91.

Jessurun J, Orr C, McNulty SN, Hagen CE, Alnajar H, Wilkes D, Kudman S, Assaad MAl, Dorsaint P, Ohara K et al..  2023.  GLI1 -Rearranged Enteric Tumor : Expanding the Spectrum of Gastrointestinal Neoplasms With GLI1 Gene Fusions.. Am J Surg Pathol. 47(1):65-73.

Bhinder B, Ferguson A, Sigouros M, Uppal M, Elsaeed AG, Bareja R, Alnajar H, Eng KWha, Conteduca V, Sboner A et al..  2023.  Immunogenomic Landscape of Neuroendocrine Prostate Cancer.. Clin Cancer Res. 29(15):2933-2943.

Assaad MAl, Gundem G, Liechty B, Sboner A, Medina J, Papaemmanuil E, Sternberg CN, Marks A, Souweidane MM, Greenfield JP et al..  2023.  The importance of escalating molecular diagnostics in patients with low-grade pediatric brain cancer.. Cold Spring Harb Mol Case Stud. 9(4)

Mendelson NL, Assaad MAl, Hadi K, Manohar J, Sigouros M, Sboner A, Medina-Martínez JS, Elemento O, Jessurun J, Mosquera JMiguel.  2023.  Whole-genome Analysis Elucidates Complex Genomic Events in GLI1 -rearranged Enteric Tumor.. Am J Surg Pathol. 47(10):1192-1193.

Kim J, Rustam S, Mosquera JMiguel, Randell SH, Shaykhiev R, Rendeiro AF, Elemento O.  2022.  Author Correction: Unsupervised discovery of tissue architecture in multiplexed imaging.. Nat Methods. 19(12):1662.

Sternberg CN, Shin N, Chernyshov K, Calabro F, Cerbone L, Procopio G, Miheecheva N, Sagaradze G, Zaichikova A, Samarina N et al..  2022.  Case report: Metastatic urothelial cancer with an exceptional response to immunotherapy and comprehensive understanding of the tumor and the tumor microenvironment.. Front Oncol. 12:1006017.

Fontugne J, Cai PY, Alnajar H, Bhinder B, Park K, Ye H, Beg S, Sailer V, Siddiqui J, Blattner-Johnson M et al..  2022.  Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci.. JCI Insight. 7(4)

Mosquera MJ, Kim S, Bareja R, Fang Z, Cai S, Pan H, Asad M, Martin MLaura, Sigouros M, Rowdo FM et al..  2022.  Extracellular Matrix in Synthetic Hydrogel-Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors.. Adv Mater. 34(2):e2100096.

van der Mijn JC, Eng KW, Chandra P, Fernandez E, Ramazanoglu S, Sigaras A, Oromendia C, Gudas LJ, Tagawa ST, Nanus DM et al..  2022.  The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapy.. Mol Oncol. 16(12):2384-2395.

Raman R, Villefranc JA, Ullmann TM, Thiesmeyer J, Anelli V, Yao J, Hurley JR, Pauli C, Bareja R, Eng KWha et al..  2022.  Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer.. J Exp Med. 219(6)

Matrai CE, Ohara K, Eng KWha, Glynn SM, Chandra P, Chatterjee-Paer S, Motanagh S, Mirabelli S, Kurtis B, He B et al..  2022.  Molecular Evaluation of Low-grade Low-stage Endometrial Cancer With and Without Recurrence.. Int J Gynecol Pathol. 41(3):207-219.

Ullmann TM, Thiesmeyer JW, Lee YJoo, Beg S, Mosquera JMiguel, Elemento O, Fahey TJ, Scognamiglio T, Houvras Y.  2022.  RET Fusion-Positive Papillary Thyroid Cancers are Associated with a More Aggressive Phenotype.. Ann Surg Oncol.

Shohdy KS, Villamar DM, Cao Y, Trieu J, Price KS, Nagy R, Tagawa ST, Molina AM, Sternberg CN, Nanus DM et al..  2022.  Serial ctDNA analysis predicts clinical progression in patients with advanced urothelial carcinoma.. Br J Cancer. 126(3):430-439.

Alnajar H, Ravichandran H, Rendeiro AFigueiredo, Ohara K, Zoughbi WAl, Manohar J, Greco N, Sigouros M, Fox J, Muth E et al..  2022.  Tumor-immune microenvironment revealed by Imaging Mass Cytometry in a metastatic sarcomatoid urothelial carcinoma with a prolonged response to pembrolizumab.. Cold Spring Harb Mol Case Stud. 8(3)

Kim J, Rustam S, Mosquera JMiguel, Randell SH, Shaykhiev R, Rendeiro AF, Elemento O.  2022.  Unsupervised discovery of tissue architecture in multiplexed imaging.. Nat Methods. 19(12):1653-1661.

Brendel M, Getseva V, Assaad MAl, Sigouros M, Sigaras A, Kane T, Khosravi P, Mosquera JMiguel, Elemento O, Hajirasouliha I.  2022.  Weakly-supervised tumor purity prediction from frozen H&E stained slides.. EBioMedicine. 80:104067.

Cyrta J, Rosiene J, Bareja R, Kudman S, Zoughbi WAl, Motanagh S, Wilkes DC, Eng K, Zhang T, Sticca E et al..  2022.  Whole-genome characterization of myoepithelial carcinomas of the soft tissue.. Cold Spring Harb Mol Case Stud. 8(7)

Zoughbi WAl, Kim D, Alperstein SAnn, Ohara K, Manohar J, Greco N, Khani F, Robinson BD, Rao RA, Elemento O et al..  2021.  Incorporating cytologic adequacy assessment into precision oncology workflow using telepathology: An institutional experience.. Cancer Cytopathol.

Beg S, Bareja R, Ohara K, Eng KWha, Wilkes DC, Pisapia DJ, Zoughbi WAl, Kudman S, Zhang W, Rao R et al..  2021.  Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology.. Transl Oncol. 14(1):100944.

Sugita M, Wilkes DC, Bareja R, Eng KW, Nataraj S, Jimenez-Flores RA, Yan LB, De Leon JPauline, Croyle JA, Kaner J et al..  2021.  Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia.. NPJ Precis Oncol. 5(1):44.

Ginter PS, McIntire PJ, Kurtis B, Mirabelli S, Motanagh S, Hoda S, Elemento O, Shin SJ, Mosquera JMiguel.  2020.  Adenomyoepithelial tumors of the breast: molecular underpinnings of a rare entity.. Mod Pathol.

Beltran H, Romanel A, Conteduca V, Casiraghi N, Sigouros M, Franceschini GMarco, Orlando F, Fedrizzi T, Ku S-Y, Dann E et al..  2020.  Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer.. J Clin Invest. 130(4):1653-1668.