Publications

Ebraheem M, Toghranegar J, Bensoussan Y, Templeton JMichael.  2026.  Explainable and Interpretable AI for Voice and Speech Analysis in Clinical Care: Systematic Review.. J Med Internet Res. 28:e83790.

Kaza S, Mohanty AS, Serpedin A, Yau J, Kim YEun, Kutler RB, Elemento O, Sulica L, Khosravi P, Rameau A.  2026.  Exploring Real-Time Tracking of Vocal Fold Polyps in Video-Stroboscopy Using Deep Learning.. Laryngoscope.

Umesh A, Cordogan S, Simpson SK, Bram JT, Jones RH, Schairer WW, Sboner A, Elemento O, Green DW, Fabricant PD.  2026.  Genetic Variants Related to TGF-β Signaling Pathway Modulate Risk of Meniscus Injury: A Multiancestry Genome-wide Association Study.. Clin Orthop Relat Res. 484(1):178-193.

Okur V, Marcus A, Falcone JN, Hurd MA, Stewart SL, Claudio K, Manohar J, Dealla F, Kumar S, Yeung M et al..  2026.  Genome sequencing identifies monogenic causes in adults with metabolic diseases.. J Endocr Soc. 10(7):bvag091.

Uppal M, Bhinder B, Marderstein AR, Batlevi CLee, Falchi L, Hamlin P, Horwitz S, Kumar A, Noy A, Zelenetz AD et al..  2026.  Integrative Molecular Analysis Reveals Determinants of Clinical Outcomes in TP53-Mutated Diffuse Large B-Cell Lymphoma.. J Clin Oncol. :JCO2501928.

Abrahimi P, Khan JF, Duren-Lubanski A, Cai W, Marouf Y, Chen N, Hirschhorn D, Mammone R, Miranda IC, Tallman JE et al..  2026.  Intravesical mesothelin-based CAR T cells targeting MUC16 effectively control bladder cancer in preclinical models.. J Exp Med. 223(7)

Anibal J, Nama GKrishna Ch, Ganesh S, Nafii Y, Cruz SSalvi, Daoud V, Zanin M, Le T, Khorrami P, Wood BJ et al..  2026.  Large Language Models for Optimizing Patient Recruitment Decisions in Voice Data Generation Projects.. Laryngoscope Investig Otolaryngol. 11(4):e70519.

Chaudhry F, Kim TWan, Elemento O, Betel D.  2026.  Machine learning analysis of population-wide plasma proteins identifies hormonal biomarkers of Parkinson's disease.. Front Aging Neurosci. 18:1730550.

Ruan J, Bond DA, Shah B, Allan JN, Rutherford SC, Gribbin C, Chen Z, Bhinder B, Tam W, Rossi D et al..  2026.  MRD-driven initial therapy of acalabrutinib and lenalidomide plus rituximab or obinutuzumab for mantle cell lymphoma.. Blood Adv. 10(4):1381-1394.

Elemento O.  2026.  Multi-Hospital Electronic Health Record Foundation Models Without Data Sharing: A Comparison of Federated Learning and Inference-Time Ensembling.. medRxiv.

Surapaneni S, Kutler RB, Setzen SA, Kim YEun, Yao P, Siddiqui SH, Pitman MJ, Sulica L, Elemento O, Khosravi P et al..  2026.  A Multimodal Approach for Deep-Learning Classification of Vocal Fold Pathologies in Stroboscopy.. Laryngoscope.

Xiao G, Annor GK, Harmon KW, Chavez V, Levine F, Ahuno S, Atmane MI, St Jean S, Rowdo FPMadorsky, Leybengrub P et al..  2026.  Mutant p53 Directs PARP to Regulate Replication Stress and Drive Breast Cancer Metastasis.. bioRxiv.

Xu C, Us I, Cohen-Setton J, Milo M, Sidders B, Fitzgibbon J, Melnick AM, Pan H, Bulusu KC, Elemento O.  2026.  PAIRWISE: Deep Learning-based Prediction of Effective Personalized Drug Combinations in Cancer.. Res Sq.

Kuo H-H, Bhinder B, Gokozan HN, Gorski K, Chandra P, Manohar J, Guevara D, Otilano J, Moyer J, Tranquille M et al..  2026.  Patient-derived organoids across cancers reveal conserved tumor heterogeneity and actionable therapeutic vulnerabilities.. Sci Adv. 12(26):eadz3351.

De Boni L, Claridge S, Nath S, Tofani K, Stein BD, Park E, Steiner S, Elemento O, Pauli C, Hopkins BD.  2026.  Placing purines in precision medicine: Targeting a metabolic reliance in KRAS-mutant tumors.. iScience. 29(3):114954.

Du W, De Boni L, Hopkins BDavid, Elemento O.  2026.  A quantitative approach for defining the degradability landscape of protein degraders.. Nat Commun.

Hanif SZ, Kutz C, Au CMCherie, Torregroza I, Palikhe S, Jannath SY, Fabiha T, Bhinder B, Washburn MP, Devost D et al..  2026.  Role of orphan G protein-coupled receptor GPR52 in breast cancer cell multicellular organization and collective invasion.. Br J Cancer.

Brieno-Enriquez M, Martinez-Marchal A, Choi E, Levy A, Chu T, Shivkumar S, Bochter J, Morales J, Walsh P, Martin-Ruiz M et al..  2026.  SARS-CoV-2 infection reduces the number of spermatogonial stem cells and dysregulates the transcriptional landscape of the human testis.. Res Sq.

Gilani A, Stein BD, Hoffmann A, de Lima RPereira, Ha EE, Homan EA, Ma L, Rubio-Navarro A, Wun TTha Ra, Carrascal GJose Ayala et al..  2026.  Secretory kinase FAM20C triggers adipocyte dysfunction, inciting insulin resistance and inflammation in obesity.. J Clin Invest. 136(1)

Nazzaro M, Mardis ER, Canella A, Bhinder B, Elemento O, Behbehani G, Currier M, Glaspell A, Lee DA, Cripe TP et al..  2026.  Trabectedin decreases myeloid resistance to improve the efficacy of anti-PD1 immunotherapy and delay glioma malignant progression.. Mol Ther Oncol. 34(1):201147.

Elemento O, Giannakakou P.  2026.  Training the Next Generation of AI-Enabled Cancer Scientists.. Cancer Discov. :OF1-OF4.

Roshal M, Kong IY, Dinalankara W, Reichel JB, Teater M, Binder B, Zairis S, Brody JD, Park SI, Kovach AE et al..  2026.  Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein response.. Blood Cancer J.

Podaza E, Capuano J, Kuo H-H, Assaad MAl, Markowitz G, M Revuelta V, Nguyen J, Irizarry A, Ravichandran H, Ackermann S et al..  2026.  Tumor immune microenvironment reconstitution in patient-derived organoids enables therapy modeling for NSCLC.. Cell Rep Methods. :101339.

Purkayastha S, Park J, Beyer S, Chandra A, Markowitz SM, Lerman BB, Elemento O, Krumsiek J, Lo JC, Cheung JW.  2026.  Utilization of Serum Metabolomics and Polygenic Risk Scores in a Novel Risk Stratification Tool for the Prediction of Incident Atrial Fibrillation.. Circ Arrhythm Electrophysiol. :e013858.

Dantas E, Hootman KC, Moyer J, Tomberlin M, Curran K, Ramesh B, Price H, Kim J, McPherson AC, Hurd MA et al..  2026.  Very low-carbohydrate ketogenic diet in treatment-naïve women with endometrial cancer and overweight: a randomized feasibility study.. Nat Commun.