Publications

Velichutina I, Shaknovich R, Geng H, Johnson NA, Gascoyne RD, Melnick AM, Elemento O.  2010.  EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis.. Blood. 116(24):5247-55.

Shaknovich R, Cerchietti L, Tsikitas L, Kormaksson M, De S, Figueroa ME, Ballon G, Yang SNing, Weinhold N, Reimers M et al..  2011.  DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation.. Blood. 118(13):3559-69.

Béguelin W, Popovic R, Teater M, Jiang Y, Bunting KL, Rosen M, Shen H, Yang SNing, Wang L, Ezponda T et al..  2013.  EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.. Cancer Cell. 23(5):677-92.

Béguelin W, Popovic R, Teater M, Jiang Y, Bunting KL, Rosen M, Shen H, Yang SNing, Wang L, Ezponda T et al..  2013.  EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.. Cancer Cell. 23(5):677-92.

Hess ME, Hess S, Meyer KD, Verhagen LAW, Koch L, Brönneke HS, Dietrich MO, Jordan SD, Saletore Y, Elemento O et al..  2013.  The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry.. Nat Neurosci. 16(8):1042-8.

Baca SC, Prandi D, Lawrence MS, Mosquera JMiguel, Romanel A, Drier Y, Park K, Kitabayashi N, MacDonald TY, Ghandi M et al..  2013.  Punctuated evolution of prostate cancer genomes.. Cell. 153(3):666-77.

Baca SC, Prandi D, Lawrence MS, Mosquera JMiguel, Romanel A, Drier Y, Park K, Kitabayashi N, MacDonald TY, Ghandi M et al..  2013.  Punctuated evolution of prostate cancer genomes.. Cell. 153(3):666-77.

Chiron D, Di Liberto M, Martin P, Huang X, Sharman J, Blecua P, Mathew S, Vijay P, Eng K, Ali S et al..  2014.  Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma.. Cancer Discov. 4(9):1022-35.

Prasain N, Lee MRyul, Vemula S, Meador JLuke, Yoshimoto M, Ferkowicz MJ, Fett A, Gupta M, Rapp BM, Saadatzadeh MReza et al..  2014.  Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells.. Nat Biotechnol. 32(11):1151-1157.

Prasain N, Lee MRyul, Vemula S, Meador JLuke, Yoshimoto M, Ferkowicz MJ, Fett A, Gupta M, Rapp BM, Saadatzadeh MReza et al..  2014.  Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells.. Nat Biotechnol. 32(11):1151-1157.

Chakravarty D, Sboner A, Nair SS, Giannopoulou E, Li R, Hennig S, Mosquera JMiguel, Pauwels J, Park K, Kossai M et al..  2014.  The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer.. Nat Commun. 5:5383.

Ceballos-Chávez M, Subtil-Rodríguez A, Giannopoulou EG, Soronellas D, Vázquez-Chávez E, Vicent GP, Elemento O, Beato M, Reyes JC.  2015.  The chromatin Remodeler CHD8 is required for activation of progesterone receptor-dependent enhancers.. PLoS Genet. 11(4):e1005174.

Ceballos-Chávez M, Subtil-Rodríguez A, Giannopoulou EG, Soronellas D, Vázquez-Chávez E, Vicent GP, Elemento O, Beato M, Reyes JC.  2015.  The chromatin Remodeler CHD8 is required for activation of progesterone receptor-dependent enhancers.. PLoS Genet. 11(4):e1005174.

Dominguez PM, Teater M, Chambwe N, Kormaksson M, Redmond D, Ishii J, Vuong B, Chaudhuri J, Melnick A, Vasanthakumar A et al..  2015.  DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.. Cell Rep. 12(12):2086-98.

Dominguez PM, Teater M, Chambwe N, Kormaksson M, Redmond D, Ishii J, Vuong B, Chaudhuri J, Melnick A, Vasanthakumar A et al..  2015.  DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.. Cell Rep. 12(12):2086-98.

Robinson D, Van Allen EM, Wu Y-M, Schultz N, Lonigro RJ, Mosquera J-M, Montgomery B, Taplin M-E, Pritchard CC, Attard G et al..  2015.  Integrative Clinical Genomics of Advanced Prostate Cancer.. Cell. 162(2):454.

Robinson D, Van Allen EM, Wu Y-M, Schultz N, Lonigro RJ, Mosquera J-M, Montgomery B, Taplin M-E, Pritchard CC, Attard G et al..  2015.  Integrative Clinical Genomics of Advanced Prostate Cancer.. Cell. 162(2):454.

Robinson D, Van Allen EM, Wu Y-M, Schultz N, Lonigro RJ, Mosquera J-M, Montgomery B, Taplin M-E, Pritchard CC, Attard G et al..  2015.  Integrative Clinical Genomics of Advanced Prostate Cancer.. Cell. 162(2):454.

Seo BRi, Bhardwaj P, Choi S, Gonzalez J, Eguiluz RCAndresen, Wang K, Mohanan S, Morris PG, Du B, Zhou XK et al..  2015.  Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis.. Sci Transl Med. 7(301):301ra130.

Seo BRi, Bhardwaj P, Choi S, Gonzalez J, Eguiluz RCAndresen, Wang K, Mohanan S, Morris PG, Du B, Zhou XK et al..  2015.  Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis.. Sci Transl Med. 7(301):301ra130.

Verma A, Jiang Y, Du W, Fairchild L, Melnick A, Elemento O.  2015.  Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma.. Genome Med. 7:110.

Beltran H, Eng K, Mosquera JMiguel, Sigaras A, Romanel A, Rennert H, Kossai M, Pauli C, Faltas B, Fontugne J et al..  2015.  Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.. JAMA Oncol. 1(4):466-74.

Culjkovic-Kraljacic B, Fernando TM, Marullo R, Calvo-Vidal N, Verma A, Yang SN, Tabbò F, Gaudiano M, Zahreddine H, Goldstein RL et al..  2016.  Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas.. Blood. 127(7):858-68.

Vazirani RP, Verma A, L Sadacca A, Buckman MS, Picatoste B, Beg M, Torsitano C, Bruno JH, Patel RT, Simonyte K et al..  2016.  Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance.. Diabetes. 65(6):1577-89.

Vazirani RP, Verma A, L Sadacca A, Buckman MS, Picatoste B, Beg M, Torsitano C, Bruno JH, Patel RT, Simonyte K et al..  2016.  Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance.. Diabetes. 65(6):1577-89.