Publications

Giannopoulou EG, Elemento O, Ivashkiv LB.  2015.  Use of RNA sequencing to evaluate rheumatic disease patients.. Arthritis Res Ther. 17:167.

Gori JL, Butler JM, Chan Y-Y, Chandrasekaran D, Poulos MG, Ginsberg M, Nolan DJ, Elemento O, Wood BL, Adair JE et al..  2015.  Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.. J Clin Invest. 125(3):1243-54.

Gori JL, Butler JM, Chan Y-Y, Chandrasekaran D, Poulos MG, Ginsberg M, Nolan DJ, Elemento O, Wood BL, Adair JE et al..  2015.  Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.. J Clin Invest. 125(3):1243-54.

Poulos MG, Crowley MJP, Gutkin MC, Ramalingam P, Schachterle W, Thomas J-L, Elemento O, Butler JM.  2015.  Vascular Platform to Define Hematopoietic Stem Cell Factors and Enhance Regenerative Hematopoiesis.. Stem Cell Reports. 5(5):881-894.

Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio IIn Christi, Giannopoulou EG, Rago C et al..  2015.  Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.. Science. 350(6266):1391-6.

Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio IIn Christi, Giannopoulou EG, Rago C et al..  2015.  Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.. Science. 350(6266):1391-6.

Beltran H, Eng K, Mosquera JMiguel, Sigaras A, Romanel A, Rennert H, Kossai M, Pauli C, Faltas B, Fontugne J et al..  2015.  Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.. JAMA Oncol. 1(4):466-74.

Beltran H, Eng K, Mosquera JMiguel, Sigaras A, Romanel A, Rennert H, Kossai M, Pauli C, Faltas B, Fontugne J et al..  2015.  Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.. JAMA Oncol. 1(4):466-74.

Israely E, Ginsberg M, Nolan D, Ding B-S, James D, Elemento O, Rafii S, Rabbany SY.  2014.  Akt suppression of TGFβ signaling contributes to the maintenance of vascular identity in embryonic stem cell-derived endothelial cells.. Stem Cells. 32(1):177-90.

Prasain N, Lee MRyul, Vemula S, Meador JLuke, Yoshimoto M, Ferkowicz MJ, Fett A, Gupta M, Rapp BM, Saadatzadeh MReza et al..  2014.  Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells.. Nat Biotechnol. 32(11):1151-1157.

Prasain N, Lee MRyul, Vemula S, Meador JLuke, Yoshimoto M, Ferkowicz MJ, Fett A, Gupta M, Rapp BM, Saadatzadeh MReza et al..  2014.  Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells.. Nat Biotechnol. 32(11):1151-1157.

Popovic R, Martinez-Garcia E, Giannopoulou EG, Zhang Q, Zhang Q, Ezponda T, Shah MY, Zheng Y, Will CM, Small EC et al..  2014.  Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.. PLoS Genet. 10(9):e1004566.

Wen D, Banaszynski LA, Liu Y, Geng F, Noh K-M, Xiang J, Elemento O, Rosenwaks Z, C Allis D, Rafii S.  2014.  Histone variant H3.3 is an essential maternal factor for oocyte reprogramming.. Proc Natl Acad Sci U S A. 111(20):7325-30.

Chakravarty D, Sboner A, Nair SS, Giannopoulou E, Li R, Hennig S, Mosquera JMiguel, Pauwels J, Park K, Kossai M et al..  2014.  The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer.. Nat Commun. 5:5383.

Chakravarty D, Sboner A, Nair SS, Giannopoulou E, Li R, Hennig S, Mosquera JMiguel, Pauwels J, Park K, Kossai M et al..  2014.  The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer.. Nat Commun. 5:5383.

De S, Shaknovich R, Riester M, Elemento O, Geng H, Kormaksson M, Jiang Y, Woolcock B, Johnson N, Polo JM et al..  2013.  Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity.. PLoS Genet. 9(1):e1003137.

De S, Shaknovich R, Riester M, Elemento O, Geng H, Kormaksson M, Jiang Y, Woolcock B, Johnson N, Polo JM et al..  2013.  Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity.. PLoS Genet. 9(1):e1003137.

Chang S-H, Lu Y-C, Li X, Hsieh W-Y, Xiong Y, Ghosh M, Evans T, Elemento O, Hla T.  2013.  Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis.. J Biol Chem. 288(7):4908-21.

Lin P-C, Chiu Y-L, Banerjee S, Park K, Mosquera JMiguel, Giannopoulou E, Alves P, Tewari AK, Gerstein MB, Beltran H et al..  2013.  Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression.. Cancer Res. 73(3):1232-44.

Lin P-C, Chiu Y-L, Banerjee S, Park K, Mosquera JMiguel, Giannopoulou E, Alves P, Tewari AK, Gerstein MB, Beltran H et al..  2013.  Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression.. Cancer Res. 73(3):1232-44.

Lin P-C, Giannopoulou EG, Park K, Mosquera JMiguel, Sboner A, Tewari AK, Garraway LA, Beltran H, Rubin MA, Elemento O.  2013.  Epigenomic alterations in localized and advanced prostate cancer.. Neoplasia. 15(4):373-83.

Lin P-C, Giannopoulou EG, Park K, Mosquera JMiguel, Sboner A, Tewari AK, Garraway LA, Beltran H, Rubin MA, Elemento O.  2013.  Epigenomic alterations in localized and advanced prostate cancer.. Neoplasia. 15(4):373-83.

Béguelin W, Popovic R, Teater M, Jiang Y, Bunting KL, Rosen M, Shen H, Yang SNing, Wang L, Ezponda T et al..  2013.  EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.. Cancer Cell. 23(5):677-92.

Bödör C, Grossmann V, Popov N, Okosun J, O'Riain C, Tan K, Marzec J, Araf S, Wang J, Lee AM et al..  2013.  EZH2 mutations are frequent and represent an early event in follicular lymphoma.. Blood. 122(18):3165-8.

Bödör C, Grossmann V, Popov N, Okosun J, O'Riain C, Tan K, Marzec J, Araf S, Wang J, Lee AM et al..  2013.  EZH2 mutations are frequent and represent an early event in follicular lymphoma.. Blood. 122(18):3165-8.