Publications

Giannopoulou E, Elemento O.  2017.  Systematic Discovery of Chromatin-Bound Protein Complexes from ChIP-seq Datasets.. Methods Mol Biol. 1507:43-58.

Park J, Foox J, Hether T, Danko D, Warren S, Kim Y, Reeves J, Butler DJ, Mozsary C, Rosiene J et al..  2021.  Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps.. bioRxiv.

Nwachukwu JC, Srinivasan S, Bruno NE, Nowak J, Wright NJ, Minutolo F, Rangarajan ES, Izard T, Yao X-Q, Grant BJ et al..  2017.  Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.. Cell Chem Biol. 24(1):35-45.

Park J, Foox J, Hether T, Danko DC, Warren S, Kim Y, Reeves J, Butler DJ, Mozsary C, Rosiene J et al..  2022.  System-wide transcriptome damage and tissue identity loss in COVID-19 patients.. Cell Rep Med. 3(2):100522.

Circosta P, Elia ARita, Landra I, Machiorlatti R, Todaro M, Aliberti S, Brusa D, Deaglio S, Chiaretti S, Bruna R et al..  2018.  Tailoring CD19xCD3-DART exposure enhances T-cells to eradication of B-cell neoplasms.. Oncoimmunology. 7(4):e1341032.

Sugita M, Wilkes DC, Bareja R, Eng KW, Nataraj S, Jimenez-Flores RA, Yan LB, De Leon JPauline, Croyle JA, Kaner J et al..  2021.  Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia.. NPJ Precis Oncol. 5(1):44.

Venturutti L, Teater M, Zhai A, Chadburn A, Babiker L, Kim D, Béguelin W, Lee TC, Kim Y, Chin CR et al..  2020.  TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate.. Cell. 182(2):297-316.e27.

Diman NYS-G, Brooks G, Kruithof BPT, Elemento O, Seidman JG, Seidman CE, Basson CT, Hatcher CJ.  2014.  Tbx5 is required for avian and Mammalian epicardial formation and coronary vasculogenesis.. Circ Res. 115(10):834-44.

Brady NJ, Bagadion AM, Singh R, Conteduca V, Van Emmenis L, Arceci E, Pakula H, Carelli R, Khani F, Bakht M et al..  2021.  Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer.. Nat Commun. 12(1):3372.

Verma N, Pan H, Doré LC, Shukla A, Li QV, Pelham-Webb B, Teijeiro V, González F, Krivtsov A, Chang C-J et al..  2018.  TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.. Nat Genet. 50(1):83-95.

Dominguez PM, Ghamlouch H, Rosikiewicz W, Kumar P, Béguelin W, Fontán L, Rivas MA, Pawlikowska P, Armand M, Mouly E et al..  2018.  TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.. Cancer Discov. 8(12):1632-1653.

Lan Y, Pan H, Li C, Banks KM, Sam J, Ding B, Elemento O, Goll MG, Evans T.  2019.  TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis.. Cell Rep. 26(3):720-732.e4.

Boi M, Todaro M, Vurchio V, Yang SNing, Moon J, Kwee I, Rinaldi A, Pan H, Crescenzo R, Cheng M et al..  2016.  Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes.. Oncotarget. 7(48):79637-79653.

Dantas E, Murthy A, Ahmed T, Ahmed M, Ramsamooj S, Hurd MA, Lam T, Malbari M, Agrusa C, Elemento O et al..  2023.  TIMP1 is an early biomarker for detection and prognosis of lung cancer.. Clin Transl Med. 13(10):e1391.

Bhinder B, Elemento O.  2017.  Towards a better cancer precision medicine: systems biology meets immunotherapy.. Curr Opin Syst Biol. 2:67-73.

Elemento O.  2021.  Towards artificial intelligence-driven pathology assessment for hematological malignancies.. Blood Cancer Discov. 2(3):195-197.

Nazzaro M, Mardis ER, Canella A, Bhinder B, Elemento O, Behbehani G, Currier M, Glaspell A, Lee DA, Cripe TP et al..  2026.  Trabectedin decreases myeloid resistance to improve the efficacy of anti-PD1 immunotherapy and delay glioma malignant progression.. Mol Ther Oncol. 34(1):201147.

Jiang Y, Elemento O.  2014.  Tracing the roots of cancer evolution.. Cancer Discov. 4(9):995-7.

Elemento O, Giannakakou P.  2026.  Training the Next Generation of AI-Enabled Cancer Scientists.. Cancer Discov. :OF1-OF4.

Gambi G, Di Simone E, Basso V, Ricci L, Wang R, Verma A, Elemento O, Ponzoni M, Inghirami G, Icardi L et al..  2019.  The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3.. Cancer Res. 79(12):3076-3087.

Choi H, Sheng J, Gao D, Li F, Durrans A, Ryu S, Lee SB, Narula N, Rafii S, Elemento O et al..  2015.  Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model.. Cell Rep. 10(7):1187-201.

Roshal M, Kong IY, Dinalankara W, Reichel JB, Teater M, Binder B, Zairis S, Brody JD, Park SI, Kovach AE et al..  2026.  Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein response.. Blood Cancer J.

Roshal M, Kong IY, Dinalankara W, Reichel JB, Teater M, Binder B, Zairis S, Brody JD, Park SI, Kovach AE et al..  2025.  Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein response.. bioRxiv.

Verma A, Jiang Y, Du W, Fairchild L, Melnick A, Elemento O.  2015.  Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma.. Genome Med. 7:110.

Shah Y, Yang H, Mueller FB, Li C, Rahim SEGul, Varma E, Salinas T, Dadhania DM, Salvatore SP, Seshan SV et al..  2024.  Transcriptomic signatures of chronic active antibody-mediated rejection deciphered by RNA sequencing of human kidney allografts.. Kidney Int. 105(2):347-363.