Publications

Markowitz GJ, Ban Y, Tavarez DA, Yoffe L, Podaza E, He Y, Martin MT, Crowley MJP, Sandoval TA, Gao D et al..  2023.  Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway and generates TCF1+ progenitor CD8+ T cells to improve checkpoint blockade.. Res Sq.

Kim YE, Dobko M, Li H, Shao T, Periyakoil P, Tipton C, Colasacco C, Serpedin A, Elemento O, Sabuncu M et al..  2025.  A Deep-Learning Model for Multi-class Audio Classification of Vocal Fold Pathologies in Office Stroboscopy.. Laryngoscope. 135(7):2428-2436.

Jiang Y, Redmond D, Nie K, Eng KW, Clozel T, Martin P, Tan LHc, Melnick AM, Tam W, Elemento O.  2014.  Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas.. Genome Biol. 15(8):432.

Page DB, Yuan J, Redmond D, Y Wen H, Durack JC, Emerson R, Solomon S, Dong Z, Wong P, Comstock C et al..  2016.  Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy.. Cancer Immunol Res. 4(10):835-844.

Courtiol P, Maussion C, Moarii M, Pronier E, Pilcer S, Sefta M, Manceron P, Toldo S, Zaslavskiy M, Le Stang N et al..  2019.  Deep learning-based classification of mesothelioma improves prediction of patient outcome.. Nat Med. 25(10):1519-1525.

Xu Z, Verma A, Naveed U, Bakhoum SF, Khosravi P, Elemento O.  2021.  Deep learning predicts chromosomal instability from histopathology images.. iScience. 24(5):102394.

Yao P, Witte D, German A, Periyakoil P, Kim YEun, Gimonet H, Sulica L, Born H, Elemento O, Barnes J et al..  2024.  A deep learning pipeline for automated classification of vocal fold polyps in flexible laryngoscopy.. Eur Arch Otorhinolaryngol. 281(4):2055-2062.

Khosravi P, Kazemi E, Zhan Q, Malmsten JE, Toschi M, Zisimopoulos P, Sigaras A, Lavery S, Cooper LAD, Hickman C et al..  2019.  Deep learning enables robust assessment and selection of human blastocysts after in vitro fertilization.. NPJ Digit Med. 2:21.

Khosravi P, Lysandrou M, Eljalby M, Li Q, Kazemi E, Zisimopoulos P, Sigaras A, Brendel M, Barnes J, Ricketts C et al..  2021.  A Deep Learning Approach to Diagnostic Classification of Prostate Cancer Using Pathology-Radiology Fusion.. J Magn Reson Imaging. 54(2):462-471.

Karimzadeh M, Momen-Roknabadi A, Cavazos TB, Fang Y, Chen N-C, Multhaup M, Yen J, Ku J, Wang J, Zhao X et al..  2024.  Deep generative AI models analyzing circulating orphan non-coding RNAs enable detection of early-stage lung cancer.. Nat Commun. 15(1):10090.

Khosravi P, Kazemi E, Imielinski M, Elemento O, Hajirasouliha I.  2018.  Deep Convolutional Neural Networks Enable Discrimination of Heterogeneous Digital Pathology Images.. EBioMedicine. 27:317-328.

Assaad MAl, Shin N, Sigouros M, Manohar J, Antysheva Z, Kotlov N, Kiriy D, Nikitina A, Kleimenov M, Tsareva A et al..  2023.  Deciphering the origin and therapeutic targets of cancer of unknown primary: a case report that illustrates the power of integrative whole-exome and transcriptome sequencing analysis.. Front Oncol. 13:1274163.

Xu C, Bulusu KC, Pan H, Elemento O.  2024.  DDI-GPT: Explainable Prediction of Drug-Drug Interactions using Large Language Models enhanced with Knowledge Graphs.. bioRxiv.

Gayvert KM, Madhukar NS, Elemento O.  2016.  A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials.. Cell Chem Biol. 23(10):1294-1301.

Liu W, Newhall KP, Khani F, Barlow LM, Nguyen D, Gu L, Eng K, Bhinder B, Uppal M, Récapet C et al..  2023.  The Cytidine Deaminase APOBEC3G Contributes to Cancer Mutagenesis and Clonal Evolution in Bladder Cancer.. Cancer Res. 83(4):506-520.

Noch EK, Palma L, Yim I, Bullen N, Barnett D, Walsh A, Bhinder B, Benedetti E, Krumsiek J, Gurvitch J et al..  2024.  Cysteine induces mitochondrial reductive stress in glioblastoma through hydrogen peroxide production.. Proc Natl Acad Sci U S A. 121(8):e2317343121.

Jiang Y, Ortega-Molina A, Geng H, Ying H-Y, Hatzi K, Parsa S, McNally D, Wang L, Doane AS, Agirre X et al..  2017.  CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.. Cancer Discov. 7(1):38-53.

Lu X, Li JM, Elemento O, Tavazoie S, Wieschaus EF.  2009.  Coupling of zygotic transcription to mitotic control at the Drosophila mid-blastula transition.. Development. 136(12):2101-10.

de la Mora JDelgado-, Assaad MAl, Karaaslan S, Hadi K, Halima A, Deshpande A, Manohar J, Sigouros M, Medina-Martínez JS, Lieberman MD et al..  2025.  Corrigendum to "Whole genome and transcriptome analysis of pancreatic acinar cell carcinoma elucidates mechanisms of homologous recombination deficiency and unravels novel relevant fusion events" [Pathol. - Res. Pract. 266 (2025) 155798].. Pathol Res Pract. 266:155825.

Huang SH, Sartorello G, Shen P-T, Xu C, Elemento O, Shvets G.  2023.  Correction: Metasurface-enhanced infrared spectroscopy in multiwell format for real-time assaying of live cells.. Lab Chip. 23(17):3893.

Lis R, Karrasch CC, Poulos MG, Kunar B, Redmond D, Duran JGBarcia, Badwe CR, Schachterle W, Ginsberg M, Xiang J et al..  2017.  Conversion of adult endothelium to immunocompetent haematopoietic stem cells.. Nature. 545(7655):439-445.

Gollamudi S, Johri A, Calingasan NY, Yang L, Elemento O, M Beal F.  2012.  Concordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human Parkinson's disease.. PLoS One. 7(5):e36191.

Benedicto I, Lehmann GL, Ginsberg M, Nolan DJ, Bareja R, Elemento O, Salfati Z, Alam NM, Prusky GT, Llanos P et al..  2017.  Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors.. Nat Commun. 8:15374.

Bhinder B, Elemento O.  2020.  Computational methods in tumor immunology.. Methods Enzymol. 636:209-259.

Gayvert KM, Dardenne E, Cheung C, Boland MRegina, Lorberbaum T, Wanjala J, Chen Y, Rubin MA, Tatonetti NP, Rickman DS et al..  2016.  A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors.. Cell Rep. 15(11):2348-56.