Publications

Pisapia DJ, Salvatore S, Pauli C, Hissong E, Eng K, Prandi D, Sailer V-W, Robinson BD, Park K, Cyrta J et al..  2017.  Next-Generation Rapid Autopsies Enable Tumor Evolution Tracking and Generation of Preclinical Models.. JCO Precis Oncol. 2017

Chang C-Y, H Pasolli A, Giannopoulou EG, Guasch G, Gronostajski RM, Elemento O, Fuchs E.  2013.  NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche.. Nature. 495(7439):98-102.

Hu Y, Bloy N, Elemento O, Buqué A.  2022.  Nicotinamide drives T cell activation in the mammary tumor microenvironment.. J Transl Med. 20(1):251.

Hissong E, Assaad MAl, Bal M, Reed KA, Fornelli A, Levine MF, Gundem G, Semaan A, Orr CE, Sakhadeo U et al..  2024.  NIPBL::NACC1 Fusion Hepatic Carcinoma.. Am J Surg Pathol. 48(2):183-193.

Dardenne E, Beltran H, Benelli M, Gayvert K, Berger A, Puca L, Cyrta J, Sboner A, Noorzad Z, MacDonald T et al..  2016.  N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.. Cancer Cell. 30(4):563-577.

Berger A, Brady NJ, Bareja R, Robinson B, Conteduca V, Augello MA, Puca L, Ahmed A, Dardenne E, Lu X et al..  2019.  N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.. J Clin Invest. 129(9):3924-3940.

Barnes J, Brendel M, Gao VR, Rajendran S, Kim J, Li Q, Malmsten JE, Sierra JT, Zisimopoulos P, Sigaras A et al..  2023.  A non-invasive artificial intelligence approach for the prediction of human blastocyst ploidy: a retrospective model development and validation study.. Lancet Digit Health. 5(1):e28-e40.

Franceschini GMarco, Quaini O, Mizuno K, Orlando F, Ciani Y, Ku S-Y, Sigouros M, Rothmann E, Alonso A, Benelli M et al..  2024.  Noninvasive Detection of Neuroendocrine Prostate Cancer through Targeted Cell-free DNA Methylation.. Cancer Discov. 14(3):424-445.

Lu Y, T Soong D, Elemento O.  2013.  A novel approach for characterizing microsatellite instability in cancer cells.. PLoS One. 8(5):e63056.

Alsaleem MA, Ball G, Toss MS, Raafat S, Aleskandarany M, Joseph C, Ogden A, Bhattarai S, Rida PCG, Khani F et al..  2020.  A novel prognostic two-gene signature for triple negative breast cancer.. Mod Pathol.

de la Mora JDelgado-, Assaad MAl, Quitian S, Levine MF, Deshpande A, Sigouros M, Manohar J, Medina-Martínez JS, Sboner A, Elemento O et al..  2025.  Novel structural variants that impact cell cycle genes are elucidated in metastatic gastrointestinal stromal tumors.. Pathol Res Pract. 266:155782.

Drozdz MM, Doane AS, Alkallas R, Desman G, Bareja R, Reilly M, Bang J, Yusupova M, You J, Eraslan Z et al..  2022.  A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation.. Cell Rep. 40(13):111412.

Takemoto A, Kawashima SA, Li J-J, Jeffery L, Yamatsugu K, Elemento O, Nurse P.  2016.  Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis.. J Cell Sci. 129(6):1250-9.

Deng Z, Loyher P-L, Lazarov T, Li L, Shen Z, Bhinder B, Yang H, Zhong Y, Alberdi A, Massague J et al..  2024.  The nuclear factor ID3 endows macrophages with a potent anti-tumour activity.. Nature. 626(8000):864-873.

Bhardwaj P, Iyengar NM, Zahid H, Carter KM, Byun DJun, Choi MHo, Sun Q, Savenkov O, Louka C, Liu C et al..  2023.  Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in .. Sci Transl Med. 15(684):eade1857.

Springer NL, Iyengar NM, Bareja R, Verma A, Jochelson MS, Giri DD, Zhou XK, Elemento O, Dannenberg AJ, Fischbach C.  2019.  Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages.. Am J Pathol. 189(10):2019-2035.

Seo BRi, Bhardwaj P, Choi S, Gonzalez J, Eguiluz RCAndresen, Wang K, Mohanan S, Morris PG, Du B, Zhou XK et al..  2015.  Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis.. Sci Transl Med. 7(301):301ra130.

Chakravarty D, Sboner A, Nair SS, Giannopoulou E, Li R, Hennig S, Mosquera JMiguel, Pauwels J, Park K, Kossai M et al..  2014.  The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer.. Nat Commun. 5:5383.

Rickman DS, T Soong D, Moss B, Mosquera JMiguel, Dlabal J, Terry S, MacDonald TY, Tripodi J, Bunting K, Najfeld V et al..  2012.  Oncogene-mediated alterations in chromatin conformation.. Proc Natl Acad Sci U S A. 109(23):9083-8.

Karass M, Bareja R, Shelkey E, Vlachostergios PJ, Robinson BD, Khani F, Mosquera JMiguel, Scherr DS, Sboner A, Tagawa ST et al..  2019.  Oncogenic Addiction to ERBB2 Signaling Predicts Response to Trastuzumab in Urothelial Cancer.. J Natl Compr Canc Netw. 17(3):194-200.

Anelli V, Villefranc JA, Chhangawala S, Martinez-McFaline R, Riva E, Nguyen A, Verma A, Bareja R, Chen Z, Scognamiglio T et al..  2017.  Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression.. Elife. 6

Elemento O, Rubin MA, Rickman DS.  2012.  Oncogenic transcription factors as master regulators of chromatin topology: a new role for ERG in prostate cancer.. Cell Cycle. 11(18):3380-3.

Kyei I, Bea VJ, Gyan KK, Adjei E, Stonaker B, Bekele M, Abebe E, Davis M, Boakye A, Boateng R et al..  2025.  Oncologic Anthropology and the African Diaspora: Twenty-Year Anniversary Report, International Center for the Study of Breast Cancer Subtypes (ICSBCS).. Ann Surg Oncol.

Kudman S, Semaan A, Assaad MAl, Gogineni S, M Martin L, Mathew S, Elemento O, Wilkes DC, Mosquera JMiguel.  2024.  Optimization of Fluorescence In Situ Hybridization Protocols in the Era of Precision Medicine.. Curr Protoc. 4(6):e1093.

Sivakumar R, Chan M, Shin JStella, Nishida-Aoki N, Kenerson HL, Elemento O, Beltran H, Yeung R, Gujral TS.  2019.  Organotypic tumor slice cultures provide a versatile platform for immuno-oncology and drug discovery.. Oncoimmunology. 8(12):e1670019.